ID H2FZX4_OCESG Unreviewed; 385 AA.
AC H2FZX4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Periplasmic component of efflux system {ECO:0000313|EMBL:AEX99872.1};
GN OrderedLocusNames=GU3_00580 {ECO:0000313|EMBL:AEX99872.1};
OS Oceanimonas sp. (strain GK1 / IBRC-M 10197).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Oceanimonas.
OX NCBI_TaxID=511062 {ECO:0000313|EMBL:AEX99872.1, ECO:0000313|Proteomes:UP000007742};
RN [1] {ECO:0000313|EMBL:AEX99872.1, ECO:0000313|Proteomes:UP000007742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GK1 {ECO:0000313|EMBL:AEX99872.1,
RC ECO:0000313|Proteomes:UP000007742};
RX PubMed=22461556; DOI=10.1128/JB.00023-12;
RA Parsa Yeganeh L., Azarbaijani R., Sarikhan S., Mousavi H., Ramezani M.,
RA Amoozegar M.A., Shahzadeh Fazeli A., Salekdeh G.H.;
RT "Complete genome sequence of Oceanimonas sp. GK1, a halotolerant bacterium
RT from Gavkhouni Wetland in Iran.";
RL J. Bacteriol. 194:2123-2124(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP003171; AEX99872.1; -; Genomic_DNA.
DR RefSeq; WP_014290609.1; NC_016745.1.
DR AlphaFoldDB; H2FZX4; -.
DR STRING; 511062.GU3_00580; -.
DR KEGG; oce:GU3_00580; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_1_6; -.
DR OrthoDB; 9791520at2; -.
DR Proteomes; UP000007742; Chromosome.
DR GO; GO:0019898; C:extrinsic component of membrane; IEA:InterPro.
DR GO; GO:1990195; C:macrolide transmembrane transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.10.140.1990; -; 1.
DR Gene3D; 6.20.50.140; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR030190; MacA_alpha-hairpin_sf.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007742}.
FT DOMAIN 60..292
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 98..173
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 385 AA; 41859 MW; 211BCB7A67962F39 CRC64;
MKKNTLMWAM PLLLVPALAL LLFYSPLFDH QAAPAPVTAA VQRGDLSDLV TATGVLQPSG
YVDVGAQVSG QLKVIHVEVG DQVGAGDLLA EIDPTVYLAQ VDASRAQLRN QRAQLKDREA
QLTLARLQHR RQQSLMADNA TSREALQSAE AGLRSAEAQV EALGAQIAQT ESSLRADEAN
LDYARIHAPM NGTVVSIEAR QGQTLNTNQQ APTLMRIADL ATMTVQAKVS EADVGKLKPG
MKVYFTTLGE PGRRWYSKLR RIEPTPVVEN NVVLYNALFD IDNPQGRLMS QMTTQVFFVR
AETEDALLVP VSALRFAGRD GRDRARITVL GNDGALQERE VRVGVSNRIQ AEVLDGLEAG
EQVVLNVAPA GEEGGARRSG MRMRF
//
