ID H2KP81_CLOSI Unreviewed; 639 AA.
AC H2KP81;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 28-JUN-2023, entry version 51.
DE SubName: Full=Cyclin-L2 {ECO:0000313|EMBL:GAA32942.1};
GN ORFNames=CLF_101475 {ECO:0000313|EMBL:GAA32942.1};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA32942.1, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA32942.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA32942.1};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cyclin family.
CC {ECO:0000256|RuleBase:RU000383}.
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DR EMBL; DF142883; GAA32942.1; -; Genomic_DNA.
DR AlphaFoldDB; H2KP81; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20533; CYCLIN_CCNL_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR043198; Cyclin/Ssn8.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10026; CYCLIN; 1.
DR PANTHER; PTHR10026:SF13; LD24704P; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 3: Inferred from homology;
KW Cyclin {ECO:0000256|RuleBase:RU000383};
KW Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT DOMAIN 60..162
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 175..259
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 321..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..415
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..455
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 72055 MW; ED1EB26DF368E838 CRC64;
MSITVTTRAK SGHADDWEYC GVKLTIHNIV IPDEKRCPTP SQLDNMDPEL ETDLRIVGCE
LIQDSGILLR LPQVALATAQ VLYQRFFYSK SFVRHFYEHY AMACIFLAAK LEECPRRIRD
VINVFHHIRQ IREQRIPTPV MLDQSYSNLK NQVIKAERRL LKELGFCVHA KHPHKLIICY
LQALEQEKNA KFVQCAWNYM NDSLRTDLFV RYLPEAIACA CIYLASCKLG IPLPRHPAWW
EMFAVDEESV REISLCLVRL YARPKPCVAE LEAELAKLRK NQMEAKEREL ELKKVPAGST
PNLGSDQGSI NVSPASVTVS EKLSLPSHDG GPLKTDEVKP FRDDRVLPPN SVLASAIATA
KAVAANISAT KGASDINRKS NSSSPTVPEH KRTSETSEPT RNDMGKKRES PETTSRKPNK
YSLDIAPGRP AAYPNVSPEP LASRKRRHPE SLTDAEHSKG NVSQNPFNQI NSRHYRRRRL
NAQESVHSTS GSDTPTSSLS PAVNAWYPFL IDRFLLLQFR SGRFVVFAAD VTPIPVAFMA
HECHGPRRSS DLLHYFTALR FRKEQVWQVA MRVKYVSIAV TQVQVASISR SANLRRDTKK
LDVSCGASCT FVNEIRVFVD VLHEGAILAL LFGLKLIEH
//
