ID H2KS10_CLOSI Unreviewed; 1194 AA.
AC H2KS10;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Structural maintenance of chromosome 1 {ECO:0000313|EMBL:GAA36806.2};
DE Flags: Fragment;
GN ORFNames=CLF_107785 {ECO:0000313|EMBL:GAA36806.2};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA36806.2, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA36806.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA36806.2};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DF143271; GAA36806.2; -; Genomic_DNA.
DR AlphaFoldDB; H2KS10; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR18937:SF12; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT DOMAIN 475..594
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT REGION 214..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 274..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 865..887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 108..144
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 356..446
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 656..740
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 960..1029
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:GAA36806.2"
SQ SEQUENCE 1194 AA; 139046 MW; 1752C0D17F2C6B0D CRC64;
KSNLMDAISF VLGENTRHLR VRRLNDLIHG SVVGKPVSKS ASVTAVYEMP DGEEIRFSRV
IHGNTSEYRI NGAAVRVDEY AAALEKIHIF MKVKNFLVFQ GAVESIAMKN ARERCQMFEE
ISKSAELKEE YDNAKLEMHM LEENTTLNLN KKKGIVAERK EAKFEIDEAE RYRKLQQDLA
LKRTELHLFK LYYNDLEIRR VREELKQREE LLASEHEQRQ SIEEEMKDKR RELGKVNRDQ
SSVEQEIKKC EQKIGKRRPE FIKVSQLLRH VTEKHKESKK SLENAKQLHS SHLQEIDQLE
AESEKISSLK REYEQQQTKK SLEQGINLEL EETQLNEYHR LKQKVAERTS HLSAVLDGLN
REYNEQKDLY DALDRRKNEI ESSLKRKETE LNENKKRLQK LMEYIESSNR AITEQRETEK
AIREEVEQAT RRIDEINTEL EAVVCQLGEA KVERHESSRA AKKQELIENL KRLFPGVHGR
LLEMCQPSHR RYQVAITKVL GKYMDAIVCD SEKTAKECIQ YMKDQRIEPE TFLPLDFLDV
KPIDERLREI SDPPNVHLVI DVIQCDPIIV KKALTFACGN ALVCETVEHA RYVAYQTGER
KKTVSLEGTL FQRSGVISGG ASDLKARARR WDEKQISTLV AKRDALQGEL KEQLKRKRKE
AELRTIQSQI KGLDTRLKYT LKDKDSTEEK LLSTNEEEMT QIARELEEVE ERLARCQTKM
QELQISVNAE KAKMDTVEDT VFHDFCVQIG VDNIRQYEDR ELRVARERDR KRLEFTNQLQ
RINNQLDYER SRDTEGAVKR WEETVAAEKI EMDKCKKQEK KVKEEMEQEE RRKTELESRL
GDLKLRAEEL DMELSEVKRR LVSKQRDIQK QQKELNQSEA RLESRRAERH SLLQSAKMED
LEIPLKPGAS PIAELESQLS ADPESLDPSS EEMARIYELE ARLPIDFKRL EKPLRQLSDD
KDVSRKAEEL QNQVDSMLNN LSRIQAPNLR AGDKLGSVEE RLRSTEAEFE DTRRRAKRAK
ARFERVRRLR YNAFMNCFLS ITDNIDPIYK SLSRNPGAQA SLLPTNAEEP YLEEIQFQCV
APGKRFQQMD SLSGGEKTIA ALALLFAMHR YNPSPFFVLD EIDAALDNTN IGKVASFIRE
YATQRAQIIV ISLKEEFYSR ADSLIGIYPD IENNCLVSRV LSFDISKYID TGEQ
//
