ID H2KTA3_CLOSI Unreviewed; 689 AA.
AC H2KTA3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 08-NOV-2023, entry version 40.
DE SubName: Full=Testis-expressed sequence 9 protein {ECO:0000313|EMBL:GAA40619.2};
GN ORFNames=CLF_112773 {ECO:0000313|EMBL:GAA40619.2};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA40619.2, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA40619.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA40619.2};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DF143801; GAA40619.2; -; Genomic_DNA.
DR AlphaFoldDB; H2KTA3; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR PANTHER; PTHR23313:SF0; TESTIS-EXPRESSED PROTEIN 9; 1.
DR PANTHER; PTHR23313; TSEC1-RELATED; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR Pfam; PF06293; Kdo; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT DOMAIN 257..328
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DOMAIN 328..689
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT COILED 89..225
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 689 AA; 77938 MW; DF56D14F34863AC4 CRC64;
MDLEVTISSK AHCTMSHRTP RTHLPIPVGG LQSKEEEYRF VFEGEIGDCC DDDVLPQPAT
KLSVNSQNRY LKAKVRALQQ EAHKVIAELN LCRDDNSQLK KRVQELEDER NRLQRLTTTH
SVQVEKVKKT LAEARTQCDV LEAERNSLKK ENETTKRATT QQATELKSAN VRLQRALDET
EKLRRELDHL RSSNRETTDS LKHTVEQLTV DNRRLERQKN ELISVFKKQL RLIDVLRRQK
MLIEASKCLQ LTEEEFLKSL DWQSSSGLID TLCFDWYKTA SSSGLRLSEN MILQAAVRIA
AEHGFENFQA SQEWLDDFLN RNQISIKGVS GTLVHQGAEA RLYSTTLYTS SSPRKCIVKE
RFVKTYRHPT LDSSLSAQRI RAEVRLLVHC RKLGLDVPAV LQVDVPSRRI WLGLIGPDAL
TLHDWFKKLA ADCVDTPTTP AGDSSPNLKH YAGVRLKHLT SALGRLLSRL HANHVVHGDL
TLANILVHKA TEEELSGSAE PRLAIIDFGL SSAVSHSAIQ RLPEEKAVDL YVFERALINA
IDMNFLSTVG KDFPQFSSPE KLMTAILDAY LDHYASQATP LRYESNENGT RCGVDSEAAL
QSEGRTNVLK LGESGWQLTH MEPSKVRCGR RIPLFVSTPQ FRISEFNREG YQSTLDISAV
VTRQQLMMPI DKNADIILSI RTMNGNKKT
//
