ID H2L345_ORYLA Unreviewed; 443 AA.
AC H2L345;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=WH2 domain-containing protein {ECO:0000259|PROSITE:PS51082};
GN Name=wipf2a {ECO:0000313|Ensembl:ENSORLP00000000152.3};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000000152.3, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000000152.3, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000000152.3,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000000152.3}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000000152.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2L345; -.
DR Ensembl; ENSORLT00000000152.3; ENSORLP00000000152.3; ENSORLG00000000122.3.
DR eggNOG; KOG4462; Eukaryota.
DR GeneTree; ENSGT00940000155557; -.
DR HOGENOM; CLU_039513_0_0_1; -.
DR OrthoDB; 5363043at2759; -.
DR TreeFam; TF332135; -.
DR Proteomes; UP000001038; Chromosome 1.
DR Bgee; ENSORLG00000000122; Expressed in testis and 14 other cell types or tissues.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR InterPro; IPR003124; WH2_dom.
DR Pfam; PF02205; WH2; 1.
DR SMART; SM00246; WH2; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 35..52
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 59..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..151
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..221
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..250
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..342
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..383
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 443 AA; 44599 MW; 6F1DB05E22951E1C CRC64;
MPIPPPPPPP GPPPPPAFNE ANNNPPKLNQ GGAKGRGALL SDIHKGAKLK KVVVNDRSAP
IIEKSGGGGS GGGGGGGGGG GGSSGGGFGG GGPMGMGGLF QGGVPKLRPV GDGPVVGSLG
RSALKPPGSR PAAPRPPTGR SSSPTPPNRP SSSEPQRSHR PSLPDISHSH NSSSSGGMKH
STSAPPPPPP FNRGNRGNAP QAPASREKPL PPTPQRAPAP SSTARPPSSS SRPQPSGSHA
PPPPPPYRPH LSGGVSNGPS DVDGGGAPEL PRRHNSLRKK HSSGGRSQAP PPPPSPSSQQ
GSRPPPPARE PPGRRAVPPA PPPSSRNGGR DAPPPPPPYR GHSSGGSEPQ IRVGKPPPPV
SSSAPPSTRT PAGPPPPPPP IRNGHSSSSS SRPNTDEFEA KFVFHPIEEL PPPDDYKPFS
KVYPSKSNKA MLRGAPPAPP VMR
//
