ID H2L709_ORYLA Unreviewed; 475 AA.
AC H2L709;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Septin {ECO:0000256|PIRNR:PIRNR006698};
GN Name=septin8a {ECO:0000313|Ensembl:ENSORLP00000001617.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000001617.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000001617.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000001617.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000001617.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000001617.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|PIRNR:PIRNR006698, ECO:0000256|RuleBase:RU004560}.
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DR AlphaFoldDB; H2L709; -.
DR STRING; 8090.ENSORLP00000001617; -.
DR Ensembl; ENSORLT00000001618.2; ENSORLP00000001617.2; ENSORLG00000001313.2.
DR eggNOG; KOG3859; Eukaryota.
DR GeneTree; ENSGT00940000156068; -.
DR InParanoid; H2L709; -.
DR OrthoDB; 5396944at2759; -.
DR TreeFam; TF101080; -.
DR Proteomes; UP000001038; Chromosome 14.
DR Bgee; ENSORLG00000001313; Expressed in gastrula and 14 other cell types or tissues.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0031105; C:septin complex; IBA:GO_Central.
DR GO; GO:0005940; C:septin ring; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0060090; F:molecular adaptor activity; IBA:GO_Central.
DR GO; GO:0061640; P:cytoskeleton-dependent cytokinesis; IBA:GO_Central.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF54; SEPTIN-8; 1.
DR Pfam; PF00735; Septin; 1.
DR PIRSF; PIRSF006698; Septin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 39..305
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT REGION 393..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..424
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 54912 MW; BB420551DCCBAC9E CRC64;
MAATDVDVFS NEEKRNLSLG GHVGFDSLPD QLVSKSVTQG FCFNILCVGE TGIGKSTLMN
TLFNTMFENE EASHYQNGVY LRPRTYDLQE SSVHLKLTIV DTVGFGDQIN KDESYKPIVD
YIDTQFENYL QEELKIKRSL FNYHDTRIHI CLYFIAPTGH SLKSLDLVTM KKLDSKVNII
PIIAKADTIS KSELHKFKIK IMSELVSNGV QIYQFPTDDE AVSEINSSMN AHLPFAVVGS
VEEVKVGNKT VRARQYPWGV VQVENESHCD FVKLREMLIR VNMEDLREQT HARHYELYRR
CKLEEMGFKD TDPDSQPISL QETYEAKRKE FLGDLQRKEE EMRQMFVNKV KETEAELKEK
EKELHDKFEH LKRIHQEEKR KVEEKRRDLE EELNTFNRRK MAAETQSLSQ PLKKDKDKKN
RSVKTENQSG VSASSSKVMM AKANVEPLNC QSWWQAIQCC TCLVHSATWR PGGIF
//
