ID H2LEN9_ORYLA Unreviewed; 644 AA.
AC H2LEN9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|PROSITE:PS50097};
GN Name=LOC111949086 {ECO:0000313|Ensembl:ENSORLP00000004415.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000004415.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000004415.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000004415.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000004415.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000004415.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2LEN9; -.
DR STRING; 8090.ENSORLP00000004415; -.
DR Ensembl; ENSORLT00000004416.2; ENSORLP00000004415.2; ENSORLG00000003547.2.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000158859; -.
DR HOGENOM; CLU_004253_14_4_1; -.
DR InParanoid; H2LEN9; -.
DR TreeFam; TF351653; -.
DR Proteomes; UP000001038; Chromosome 2.
DR Bgee; ENSORLG00000003547; Expressed in muscle tissue and 8 other cell types or tissues.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR CDD; cd18341; BTB_POZ_KLHL41_KBTBD10; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR030571; KLHL41_KL41B_BTB_POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 4.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 4.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..644
FT /note="BTB domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017195813"
FT DOMAIN 74..143
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 308..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 73000 MW; 28FD2D2FFADE24C7 CRC64;
MLLTLWELLL SHAGHFLFAS QPSSNAARPP SCFNGRDPSR HAMDPNAIKE ELRLFQSTLL
QDGLKELLNE NKFVDCTLKV GDRSFPCHRL IIAACSPYFR EIFFTEDGKE VEDTKEVILE
DVNPSILDMI IQYLYSAEID LTDDNVQDII AVANRFQIPS VFTVCVNYLQ KKLSLSNCMA
IFRMGLVLGC PRLAVSARNY IADRFEFLHK EEEFLKLAAH EMFAIVGGDS LNVEKEEMVF
EAVMAWVRHD REKRVKFLKD AFNCIRFRLL PEKYFKEKVE TDEIVKGDPE LQKTIQVIRD
AFKGKLPEKA KKKDGEEGGE EEESPFPGFL NDTRRQGMHA RDFILMINDT AAVAYDVGEN
ECFLAAMSEQ VPRNHVSLVS QKNQLYIIGG LFVDEENKDA PLQCYFYLFD PLSADWMALP
PMPSPRCLFN IGESDNLMFA VAGKDLQTNE SLDSVMCYDT EKMKWSETKK LPLKIHGHAV
VSHKGLVYCI GGKTDDNKAL NKMFSYNHKQ SEWREMAAMK TPRAMFGATI HKGKIVVAGG
VNEEGLSAAC EAFDFATNKW EPFTEFPQER SSINLVSNGG SLYAVGGFAM VQMENKEVAP
TEVTDVWLYE EDKKQWSGML REMRYAAGSS CACMRLNAAR MPKL
//
