ID H2MIJ6_ORYLA Unreviewed; 166 AA.
AC H2MIJ6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Ribonuclease P/MRP protein subunit POP5 {ECO:0000256|ARBA:ARBA00044198, ECO:0000256|PIRNR:PIRNR023803};
GN Name=pop5 {ECO:0000313|Ensembl:ENSORLP00000018478.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000018478.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000018478.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000018478.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000018478.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000018478.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of ribonuclease P, a protein complex that generates
CC mature tRNA molecules by cleaving their 5'-ends.
CC {ECO:0000256|PIRNR:PIRNR023803}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|PIRNR:PIRNR023803}.
CC -!- SIMILARITY: Belongs to the eukaryotic/archaeal RNase P protein
CC component 2 family. {ECO:0000256|ARBA:ARBA00010800,
CC ECO:0000256|PIRNR:PIRNR023803}.
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DR RefSeq; XP_004072603.1; XM_004072555.2.
DR AlphaFoldDB; H2MIJ6; -.
DR STRING; 8090.ENSORLP00000018478; -.
DR Ensembl; ENSORLT00000018479.2; ENSORLP00000018478.1; ENSORLG00000014745.2.
DR GeneID; 101166229; -.
DR KEGG; ola:101166229; -.
DR CTD; 51367; -.
DR eggNOG; KOG4639; Eukaryota.
DR GeneTree; ENSGT00390000012331; -.
DR HOGENOM; CLU_086710_2_0_1; -.
DR InParanoid; H2MIJ6; -.
DR OMA; MQNYLDK; -.
DR OrthoDB; 2787248at2759; -.
DR TreeFam; TF317496; -.
DR Proteomes; UP000001038; Chromosome 9.
DR Bgee; ENSORLG00000014745; Expressed in animal zygote and 14 other cell types or tissues.
DR GO; GO:0005655; C:nucleolar ribonuclease P complex; IBA:GO_Central.
DR GO; GO:0000172; C:ribonuclease MRP complex; IBA:GO_Central.
DR GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-EC.
DR GO; GO:0033204; F:ribonuclease P RNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR GO; GO:0001682; P:tRNA 5'-leader removal; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IBA:GO_Central.
DR Gene3D; 3.30.70.3250; Ribonuclease P, Pop5 subunit; 1.
DR InterPro; IPR002759; Pop5/Rpp14/Rnp2-like.
DR InterPro; IPR016819; RNase_P/MRP_POP5.
DR InterPro; IPR038085; Rnp2-like_sf.
DR PANTHER; PTHR48326; RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5; 1.
DR PANTHER; PTHR48326:SF1; RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5; 1.
DR Pfam; PF01900; RNase_P_Rpp14; 1.
DR PIRSF; PIRSF023803; Ribonuclease_P_prd; 1.
DR SUPFAM; SSF160350; Rnp2-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR023803};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694,
KW ECO:0000256|PIRNR:PIRNR023803}.
SQ SEQUENCE 166 AA; 18846 MW; 35F99B361096E011 CRC64;
MVRVKSRYLL CEVNVSESRD LLLLDDRAVA GAVRSAVARM HGDYGAALCS IRLSVKYLNV
HNGMVFLRFP KSCYQLLWSA LPFITNIESR GQQIPCFLNC LHVGGTIRTC QKFLIRYNTQ
QLQRILPKCK NAAEKDQVCQ EILNCLPTRG SKPTYEGGSE FEDERE
//
