ID H2MLT5_ORYLA Unreviewed; 280 AA.
AC H2MLT5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Cerebellin 20 {ECO:0000313|Ensembl:ENSORLP00000019670.2};
GN Name=LOC101168564 {ECO:0000313|Ensembl:ENSORLP00000019670.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000019670.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000019670.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000019670.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000019670.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000019670.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2MLT5; -.
DR Ensembl; ENSORLT00000019671.2; ENSORLP00000019670.2; ENSORLG00000015708.2.
DR eggNOG; ENOG502QU65; Eukaryota.
DR GeneTree; ENSGT00940000163520; -.
DR HOGENOM; CLU_001074_8_1_1; -.
DR InParanoid; H2MLT5; -.
DR Proteomes; UP000001038; Chromosome 13.
DR Bgee; ENSORLG00000015708; Expressed in sexually immature organism and 4 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR22923; CEREBELLIN-RELATED; 1.
DR PANTHER; PTHR22923:SF103; COMPLEMENT C1Q-LIKE PROTEIN 4; 1.
DR Pfam; PF00386; C1q; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 135..280
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 280 AA; 30289 MW; 9F9CC094E98E468F CRC64;
MTLFQKNRTL EGGARPKEEE QNSEAKGREN YKSILSFPEL SSGSHLAVPL KLIFSSNMRA
VALLCLLCVS ADGQYNWDGP GRVGPDSSNA CTVDQASCGC CLMLQEMNRL KTYFDTTLTD
IEEDFRKTNQ SLSTLKAKRV AFTAALYSGD NFKCYGPFTT NSVIIYKQMF LNLGGAYSTD
TGLLTVPFSG VYSLAVTSYS DSGSPGFTLA ICSSLQVNGK TVAAAKDFNT NDKEDSATIA
VALQLTAGDK VSVSLTRGCF LCDDSSHYNT FSAFLLYATE
//
