ID H2MQX0_ORYLA Unreviewed; 1049 AA.
AC H2MQX0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSORLP00000021144.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000021144.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000021144.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000021144.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000021144.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000021144.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR AlphaFoldDB; H2MQX0; -.
DR STRING; 8090.ENSORLP00000021144; -.
DR Ensembl; ENSORLT00000021145.2; ENSORLP00000021144.2; ENSORLG00000016886.2.
DR eggNOG; KOG1836; Eukaryota.
DR eggNOG; KOG3516; Eukaryota.
DR GeneTree; ENSGT00940000155638; -.
DR HOGENOM; CLU_000301_1_0_1; -.
DR InParanoid; H2MQX0; -.
DR TreeFam; TF335359; -.
DR Proteomes; UP000001038; Chromosome 17.
DR Bgee; ENSORLG00000016886; Expressed in pharyngeal gill and 12 other cell types or tissues.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProt.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 2.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.200; -; 5.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR010307; Laminin_dom_II.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR15036:SF49; AXOTACTIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00053; Laminin_EGF; 2.
DR Pfam; PF02210; Laminin_G_2; 3.
DR Pfam; PF06009; Laminin_II; 1.
DR SMART; SM00180; EGF_Lam; 2.
DR SMART; SM00282; LamG; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 2.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 37..83
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 84..133
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 764..930
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 511..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 170..237
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 281..338
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 56..65
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 104..113
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1049 AA; 116689 MW; A89C83B439F86422 CRC64;
MGSEDTLPFA SRPGISKCSA GFYRDAIGSF LGRCVPCQCN GLASECEDKT GRCLNCRYNT
AGDRCEHCKE GYYGNAALRT CRACPCPFSE SGNKEVNGNI NCVCKPGYTG ERCERCSSGY
FGDPMSPGGR CQPCNCNGNG NNCDPRTGAK SDLTTKVKKI TNAAAQKDIV EAAEEHANNL
AKLAKDLENA VKNASGRSEV RDARDSIEAY QNITDAINAA EAAANEAKEA ADNALKVGGT
LDVLFIHKEV NKNDLSPFFN RFVWGFFDHV FFSPDDIKEK IEEAKRKAAA VNETTKKTME
KLNNISNEIN KINISPSHSN LSNELKDMNQ SVNQLLKIIP SLNDKIAEVE NVTAKFPPTN
NISDSIKNVK ELIEQARDAA NRITIPMNFK GDGYVELRPP KDLDDLKAYT SLSLKLQRPL
GRGDGKRRRR QAVKDEDMFV MYLGKRDSSK NYIGMVLRKS ILYTVYKLNS VEYELKSSYV
IRSASEPAKF DRVDLHRSIY QDAEIIYTSD VTSNTPGQPV STSSQGTQNK DLLNISPSDV
VFYVGGYPAN FTPPASLNLP KYQGCLELIS FNDKVVSLYN FQKAERINPE IPCKRYLPPV
DSDYYEGTGY GKVALTLRST TVLVISMSVR ARSENALLSF LQMTDWTDIQ IIVKTNIEVQ
IRVTSSLAFK TEVKFNIPDF QEFYVGGIPQ GLREKNNITM QPFLGCIKNL KVFSDFQVLQ
EQVGVSKGCP ILRKAQFSLG SSLSSNLPGF SLDKDLTLSL GFKSKEPEGA QTHPCIPRSL
KGVMCMIFCL CRPHFSLDVR TRSAEGLLFF AATRGGRSHL VLYMSKGRIR LSVGKQKEIF
NREKYNDGRW HSVIFTFEKR KFRLVVDGIR AQDGQLSNAE LKSMQEFMSP VFLGSSKDLP
KHSVSGCLRN FKMNGALMSN PTTNTGAGPC FEGQTQRGVY FSGNGAHVIL IKCLLRMTRK
DYLFNRHYLF RGEFMVSVKP KTSLCDGVFH KISVIKRLHV VQLSVDTMDN YKIGPPTSTP
ILTKSPLFLG GIPGECPKMY KIPNLPHKL
//
