ID H2MQY3_ORYLA Unreviewed; 829 AA.
AC H2MQY3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Scm like with four mbt domains 2 {ECO:0000313|Ensembl:ENSORLP00000021157.2};
GN Name=SFMBT2 {ECO:0000313|Ensembl:ENSORLP00000021157.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000021157.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000021157.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000021157.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000021157.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000021157.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; H2MQY3; -.
DR Ensembl; ENSORLT00000021158.2; ENSORLP00000021157.2; ENSORLG00000016910.2.
DR eggNOG; KOG3766; Eukaryota.
DR GeneTree; ENSGT00940000158123; -.
DR HOGENOM; CLU_005352_0_0_1; -.
DR TreeFam; TF316498; -.
DR Proteomes; UP000001038; Chromosome 23.
DR Bgee; ENSORLG00000016910; Expressed in mesonephros and 14 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042393; F:histone binding; IEA:InterPro.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR CDD; cd09581; SAM_Scm-like-4MBT1_2; 1.
DR Gene3D; 2.30.30.140; -; 4.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR037604; Scm-like-4MBT1/2_SAM.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF62; SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 2; 1.
DR Pfam; PF02820; MBT; 4.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00561; MBT; 4.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 4.
DR PROSITE; PS51079; MBT; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 11..111
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 119..222
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 226..325
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 333..429
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 756..822
FT /note="SAM"
FT /evidence="ECO:0000259|SMART:SM00454"
FT REGION 614..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 701..734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 829 AA; 93256 MW; E45B703B4CB1FA0F CRC64;
SPPNQTDEAE FNWEEYLEET GAEAAPHTTF RHVEISLQSS FQPGMKLEVA NKGSPDTYWV
ASIITTCGQL LLLRYSGYGE DRKADFWCDV MTAELHPVGW CAQNNKTLMP PQAIKDKFSD
WTEFLIQDLT GSQTAPANLL EGPLRGKNTV DLIQEGSVLE LQDLSDPFLY WPVRVVQNVG
GRLRLRYAGL SEEDRDFWLF YLDVRLRPLS WALENHLKLE TPSLMTCMEL FFIKGGAGWS
KLVVFPRQDH VDLPKHSFRT GMKLEIVSRW EQLQICPVSV TKVTQVTLDD LSEGAERRSV
VCHASLPGIL PVQWCLKNGV ALEKPRGYEG QDFDWADYLK QSGTEAAPES CFPDTWHNRG
FAKDMWLEAV NPQRPAEVCV AQIIQVRGRL LWLRLEGTDP LSECIVDVDS MDIFPVGWCE
ANSYPLTSPL KPVCQKQVAV VQPEKHFVPP ETLVSALLGV SGSANGRYCC SKIFVNHRCF
SGPYLNKGRI AELPQAVGPG KCTLVLKEML SMLVNSAYKP GRVLKELQEL EDQSWDCQEE
TLKAKYKGKT YRSTIRTVRL AEQIPDFCQK VCLKLQCCPN LFSPALVTDK CPENCSVQTK
TKYTYYYGKK RKLPKPGGGE EALGEEPTKP ARRRKKRKAI FVQKKRRSSA VDFTSAGEDD
EDAALQSGSE ATSSEPRDDH TDASSVEINS SRPRRAATLR RAVSTGNSAF SQEAATGPRR
STRSLSSYNQ NNTKYELTKE EDAEEEEAQL VLDRNPLDWS VDEVVQFISS TDCASLANIF
REQDIDGQAL LLLTLPTVQE CMDLKLGPAI KLCHQIERVK VAFYRQYAN
//
