ID H2P0Z2_PONAB Unreviewed; 672 AA.
AC H2P0Z2; A0A2J8SU57; A0A6D2WQR7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=GPCPD1 isoform 1 {ECO:0000313|EMBL:PNJ24318.1};
DE SubName: Full=Glycerophosphocholine phosphodiesterase 1 {ECO:0000313|Ensembl:ENSPPYP00000011948.2};
GN Name=GPCPD1 {ECO:0000313|Ensembl:ENSPPYP00000011948.2};
GN ORFNames=CR201_G0040460 {ECO:0000313|EMBL:PNJ24318.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000011948.2, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000011948.2, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ24318.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ24318.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000011948.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC family. {ECO:0000256|ARBA:ARBA00007277}.
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DR EMBL; NDHI03003544; PNJ24318.1; -; Genomic_DNA.
DR RefSeq; XP_009231562.1; XM_009233287.1.
DR RefSeq; XP_009231563.1; XM_009233288.1.
DR STRING; 9601.ENSPPYP00000011948; -.
DR Ensembl; ENSPPYT00000012419.3; ENSPPYP00000011948.2; ENSPPYG00000010687.3.
DR GeneID; 100457313; -.
DR KEGG; pon:100457313; -.
DR CTD; 56261; -.
DR eggNOG; KOG2421; Eukaryota.
DR GeneTree; ENSGT00440000033970; -.
DR HOGENOM; CLU_013007_2_0_1; -.
DR OMA; LKVYHTA; -.
DR OrthoDB; 1005457at2759; -.
DR TreeFam; TF314722; -.
DR Proteomes; UP000001595; Chromosome 20.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:2001070; F:starch binding; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd05814; CBM20_Prei4; 1.
DR CDD; cd08607; GDPD_GDE5; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR013784; Carb-bd-like_fold.
DR InterPro; IPR034839; CBM20_GPCPD1.
DR InterPro; IPR002044; CBM_fam20.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR22958:SF1; GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1; 1.
DR PANTHER; PTHR22958; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF00686; CBM_20; 1.
DR Pfam; PF03009; GDPD; 1.
DR SMART; SM01065; CBM_2; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR SUPFAM; SSF49452; Starch-binding domain-like; 1.
DR PROSITE; PS51166; CBM20; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT DOMAIN 1..115
FT /note="CBM20"
FT /evidence="ECO:0000259|PROSITE:PS51166"
FT DOMAIN 318..618
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 672 AA; 75997 MW; 1E7D51BBEC811F02 CRC64;
MTPSQVAFEI RGSLLPGEVF AICGSCDALG NWNPQNAVAL LPENDTGESM LWKATIVLSR
GVSVQYRYFK GYFLEPKTFG GPCQVIVHKW ETHLQPRSIT PLESEIIIDD GQFGIHNGVE
TLDSGWLTCQ TEIRLRLHYS EKPPVSITKK KLKKSRFRVK LTLEGLEEDD DDRVSPTVLH
KMSNSLEISL ISDNEFKCRH SQPECGYGLQ PDRWTEYSIQ TMEPDNLELI FDFFEEDLSE
HVVQGDALPG HVGTACLLSS TIAESGKSAG ILTLPIMSRN SRKTIGKVRV DYIIIKPLPG
YSCGMKSSFS KYWKPRIPLD VGHRGAGNST TTAQLAKVQE NTIASLRNAA SHGAAFVEFD
VHLSKDFVPV VYHDLTCCLT MKKKFDADPV ELFEIPVKEL TFDQLQLLKL THVTALKSKD
RKESVVQEEN SFSENQPFPS LKMVLESLPE DVGFNIEIKW ICQQRDGMWD GNLSTYFDMN
LFLDIILKTV LENSGKRRIV FSSFDADICT MVRQKQNKYP ILFLTQGKSE IYPELMDLRS
RTTPIAMSFA QFENLLGINV HTEDLLRNPS YIQEAKAKGL VIFCWGDDTN DPENRRKLKE
LGVNGLIYDR IYDWMPEQPN IFQVEQLERL KQELPELKSC LCPTVSRFVP SSLCGESDIH
VDANGIDNVE NA
//
