ID H2P1T0_PONAB Unreviewed; 576 AA.
AC H2P1T0; A0A2J8VJD2; A0A2J8VJF7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=CNBD2 isoform 4 {ECO:0000313|EMBL:PNJ57638.1};
DE SubName: Full=Cyclic nucleotide binding domain containing 2 {ECO:0000313|Ensembl:ENSPPYP00000012244.2};
GN Name=CNBD2 {ECO:0000313|Ensembl:ENSPPYP00000012244.2};
GN ORFNames=CR201_G0018672 {ECO:0000313|EMBL:PNJ57638.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000012244.2, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000012244.2, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ57638.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ57638.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000012244.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; NDHI03003419; PNJ57638.1; -; Genomic_DNA.
DR RefSeq; XP_009231827.1; XM_009233552.1.
DR STRING; 9601.ENSPPYP00000012244; -.
DR Ensembl; ENSPPYT00000012725.2; ENSPPYP00000012244.2; ENSPPYG00000010966.2.
DR eggNOG; KOG1113; Eukaryota.
DR GeneTree; ENSGT00390000003964; -.
DR HOGENOM; CLU_033437_0_0_1; -.
DR OrthoDB; 5397097at2759; -.
DR TreeFam; TF326269; -.
DR Proteomes; UP000001595; Chromosome 20.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR InterPro; IPR043533; CNBD1/2.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR23011:SF44; CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR23011; UNCHARACTERIZED; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT DOMAIN 116..218
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 576 AA; 67655 MW; 1DB501AD6B012397 CRC64;
MRRYMVTYAW QLLKKELGLY QLATDIIIMI RVCKMFRQGL RGFREYQIIE TAHWKHPIFS
FWDKKTQSRV TFDTMDFIAE EDHFPPKAIQ IMQKKPSWRT EDEIQAVCNI LQVLDSYRNY
AEPLQLLLAK VMRFERFGRR RVIIKKGQKG NSFYFIYLGT VAITKDEDGS SAFLDPHPKL
LHKGSCFGET DVLHASMRRS TIVCMEETEF LVVDREDFFA NKLDHEVQKD AQYRFEFFRK
MDLFASWSDE KLWQLVTMAK IERFSYGQLI SKDFGESPFI MFISKGSCEV LRLLDLGASP
SYRRWVWQHL ELIDDRPLKT HLSEYSPMER FKEFQIKSYP LQDFSSLKLL HLKKAWGLQG
TSFSRKIRTS GDTLPKMLGP KIQSRPAQSI KCAMINTKLG ELPKEAAVGA YVKVHTVEQG
EILGLHQVFL PEGECDTRPL ILMSLGNELI RIRKEIFYEL IDNDDKMIKK LLKLNIAFPS
DEDMCQKFLQ ENSWNIFRKD LLRLLVEPCQ SQLFTPNRPK KKEIYNPKSV VLDLCSINKT
TKPRYPIFMA PQKYLPPLRI VQAIKAPRYK IRELLA
//
