ID H2QH69_PANTR Unreviewed; 206 AA.
AC H2QH69; A0A2J8IWR0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Probable N-acetyltransferase 14 {ECO:0000256|ARBA:ARBA00040241};
GN Name=NAT14 {ECO:0000313|EMBL:JAA02037.1,
GN ECO:0000313|Ensembl:ENSPTRP00000019800.3, ECO:0000313|VGNC:VGNC:7788};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000019800.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000019800.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA02037.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA02037.1}, and Smooth
RC vascular {ECO:0000313|EMBL:JAA11498.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000019800.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Probable acetyltransferase. {ECO:0000256|ARBA:ARBA00037582}.
CC -!- SIMILARITY: Belongs to the camello family.
CC {ECO:0000256|ARBA:ARBA00038470}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACZ04002217; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01009301; JAA02037.1; -; mRNA.
DR EMBL; GABF01010647; JAA11498.1; -; mRNA.
DR RefSeq; XP_001135806.1; XM_001135806.5.
DR STRING; 9598.ENSPTRP00000019800; -.
DR PaxDb; 9598-ENSPTRP00000019800; -.
DR Ensembl; ENSPTRT00000021456.4; ENSPTRP00000019800.3; ENSPTRG00000011512.4.
DR GeneID; 736425; -.
DR KEGG; ptr:736425; -.
DR CTD; 57106; -.
DR VGNC; VGNC:7788; NAT14.
DR eggNOG; ENOG502RYNT; Eukaryota.
DR GeneTree; ENSGT00950000182932; -.
DR HOGENOM; CLU_127402_0_0_1; -.
DR OMA; RWHRRQG; -.
DR OrthoDB; 5360516at2759; -.
DR TreeFam; TF336981; -.
DR Proteomes; UP000002277; Chromosome 19.
DR Bgee; ENSPTRG00000011512; Expressed in superior frontal gyrus and 16 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008080; F:N-acetyltransferase activity; IBA:GO_Central.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR000182; GNAT_dom.
DR PANTHER; PTHR13947; GNAT FAMILY N-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR13947:SF37; N-ACETYLTRANSFERASE 14-RELATED; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51186; GNAT; 1.
PE 2: Evidence at transcript level;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Transferase {ECO:0000313|EMBL:JAA02037.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..206
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 206 AA; 21664 MW; EA8CF3AD64641916 CRC64;
MAPSHLSVRE MREDEKPLVL EMLKAGVKDT ENRVALHALT RPPALLLLAA ASSGLRFVLA
SFALALLLPV FLAVAAVKLG LRARWGSLPP PGGLGGPWVA VRGSGDVCGV LALAPGTNAG
DGARVTRLSV SRWHRRRGVG RRLLAFAEAR ARAWAGGMGE PRARLVVPVA VAAWGVAGML
EGCGYQAEGG WGCLGYTLVR EFSKDL
//
