ID H2QHZ0_PANTR Unreviewed; 397 AA.
AC H2QHZ0; A0A2J8N3P4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};
GN Name=B3GNT2 {ECO:0000313|EMBL:JAA07373.1,
GN ECO:0000313|Ensembl:ENSPTRP00000061455.1, ECO:0000313|VGNC:VGNC:170};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000061455.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000061455.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA07373.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA07373.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA43865.1}, Skin {ECO:0000313|EMBL:JAA24984.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA13191.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000061455.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein
CC {ECO:0000256|RuleBase:RU363063}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661, ECO:0000256|RuleBase:RU363063}.
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DR EMBL; AACZ04063520; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01003965; JAA07373.1; -; mRNA.
DR EMBL; GABF01008954; JAA13191.1; -; mRNA.
DR EMBL; GABD01008116; JAA24984.1; -; mRNA.
DR EMBL; GABE01000874; JAA43865.1; -; mRNA.
DR RefSeq; XP_001152203.2; XM_001152203.5.
DR STRING; 9598.ENSPTRP00000061455; -.
DR PaxDb; 9598-ENSPTRP00000020550; -.
DR Ensembl; ENSPTRT00000087327.1; ENSPTRP00000061455.1; ENSPTRG00000051560.1.
DR GeneID; 745838; -.
DR KEGG; ptr:745838; -.
DR CTD; 10678; -.
DR VGNC; VGNC:170; B3GNT2.
DR eggNOG; KOG2287; Eukaryota.
DR GeneTree; ENSGT00940000155345; -.
DR HOGENOM; CLU_036849_5_0_1; -.
DR OMA; VSHLNYC; -.
DR OrthoDB; 532757at2759; -.
DR TreeFam; TF318639; -.
DR Proteomes; UP000002277; Chromosome 2A.
DR Bgee; ENSPTRG00000051560; Expressed in lung and 21 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0008532; F:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; IBA:GO_Central.
DR GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR GO; GO:1990830; P:cellular response to leukemia inhibitory factor; IEA:Ensembl.
DR GO; GO:0030311; P:poly-N-acetyllactosamine biosynthetic process; IEA:Ensembl.
DR GO; GO:0006493; P:protein O-linked glycosylation; IBA:GO_Central.
DR GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR002659; Glyco_trans_31.
DR PANTHER; PTHR11214; BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR11214:SF25; N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 2; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
PE 2: Evidence at transcript level;
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363063,
KW ECO:0000313|EMBL:JAA07373.1};
KW Golgi apparatus {ECO:0000256|RuleBase:RU363063};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363063};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968,
KW ECO:0000256|RuleBase:RU363063};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:JAA07373.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363063};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363063}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363063"
SQ SEQUENCE 397 AA; 46022 MW; B104ECCAE26DC4AC CRC64;
MSVGRRRIKL LGILMMANVF IYFIMEVSKS SSQEKNGKGE VIIPKEKFWK ISTPPEAYWN
REQEKLNRQY NPILSMLTNQ TGEAGRLSNI SHLNYCEPDL RVTSVVTGFN NLPDRFKDFL
LYLRCRNYSL LIDQPDKCAK KPFLLLAIKS LTPHFARRQA IRESWGQESN AGNQTVVRVF
LLGQTPPEDN HPDLSDMLKF ESEKHQDILM WNYRDTFFNL SLKEVLFLRW VSTSCPDTEF
VFKGDDDVFV NTHHILNYLN SLSKTKAKDL FIGDVIHNAG PHRDKKLKYY IPEVVYSGLY
PPYAGGGGFL YSGHLALRLY HITDQVHLYP IDDVYTGMCL QKLGLVPEKH KGFRTFDIEE
KNKNNICSYV DLMLVHSRKP QEMIDIWSQL QSAHLKC
//
