ID H2QI13_PANTR Unreviewed; 185 AA.
AC H2QI13;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Gastrokine 1 {ECO:0000313|Ensembl:ENSPTRP00000020621.4};
GN Name=GKN1 {ECO:0000313|Ensembl:ENSPTRP00000020621.4,
GN ECO:0000313|VGNC:VGNC:10653};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000020621.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000020621.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000020621.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04063556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2QI13; -.
DR PaxDb; 9598-ENSPTRP00000020621; -.
DR Ensembl; ENSPTRT00000022344.4; ENSPTRP00000020621.4; ENSPTRG00000012010.4.
DR VGNC; VGNC:10653; GKN1.
DR eggNOG; ENOG502S4AB; Eukaryota.
DR GeneTree; ENSGT00930000150969; -.
DR HOGENOM; CLU_098684_2_0_1; -.
DR InParanoid; H2QI13; -.
DR OMA; HNVANID; -.
DR TreeFam; TF335950; -.
DR Proteomes; UP000002277; Chromosome 2A.
DR Bgee; ENSPTRG00000012010; Expressed in colon.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0030141; C:secretory granule; IEA:Ensembl.
DR GO; GO:0008083; F:growth factor activity; IEA:Ensembl.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0042127; P:regulation of cell population proliferation; IBA:GO_Central.
DR Gene3D; 3.30.390.150; -; 1.
DR InterPro; IPR007084; BRICHOS_dom.
DR PANTHER; PTHR16483; GASTROKINE 1; 1.
DR PANTHER; PTHR16483:SF1; GASTROKINE-1; 1.
DR Pfam; PF04089; BRICHOS; 1.
DR SMART; SM01039; BRICHOS; 1.
DR PROSITE; PS50869; BRICHOS; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..185
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014181423"
FT DOMAIN 54..150
FT /note="BRICHOS"
FT /evidence="ECO:0000259|PROSITE:PS50869"
SQ SEQUENCE 185 AA; 20389 MW; 527502BBB904A1D5 CRC64;
MKFTIVFAGL LGVFLTPALA NYNINVNDDN NNAGSGQQSV SINNEHNVAN VDNNNGWDSW
NSIWDYGNGF AATRLFQKKT CIVHKMNKEV MPSIQSLDAL VKEKKLQGKG PGGPPPKGLM
YSVNPNKVDD LSKFGKNIAN MCRGIPTYMA EEMQEASLFF YSGTCYTTSI LWIVDISFCG
DTVEN
//
