ID H2QRR8_PANTR Unreviewed; 494 AA.
AC H2QRR8; A0A2J8NJE4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Prenylcysteine oxidase 1 like {ECO:0000313|EMBL:JAA08860.1, ECO:0000313|Ensembl:ENSPTRP00000029730.4};
GN Name=PCYOX1L {ECO:0000313|EMBL:JAA08860.1,
GN ECO:0000313|Ensembl:ENSPTRP00000029730.4, ECO:0000313|VGNC:VGNC:4122};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000029730.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000029730.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA08860.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA08860.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA35125.1}, Skin {ECO:0000313|EMBL:JAA27772.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA20023.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000029730.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRNR:PIRNR036292};
CC -!- SIMILARITY: Belongs to the prenylcysteine oxidase family.
CC {ECO:0000256|ARBA:ARBA00009967, ECO:0000256|PIRNR:PIRNR036292}.
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DR EMBL; AACZ04059121; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01002478; JAA08860.1; -; mRNA.
DR EMBL; GABF01002122; JAA20023.1; -; mRNA.
DR EMBL; GABD01005328; JAA27772.1; -; mRNA.
DR EMBL; GABE01009614; JAA35125.1; -; mRNA.
DR RefSeq; XP_001163338.1; XM_001163338.3.
DR STRING; 9598.ENSPTRP00000029730; -.
DR PaxDb; 9598-ENSPTRP00000029730; -.
DR Ensembl; ENSPTRT00000032184.5; ENSPTRP00000029730.4; ENSPTRG00000017397.5.
DR GeneID; 741792; -.
DR KEGG; ptr:741792; -.
DR CTD; 78991; -.
DR VGNC; VGNC:4122; PCYOX1L.
DR eggNOG; ENOG502QSHJ; Eukaryota.
DR GeneTree; ENSGT00390000011206; -.
DR HOGENOM; CLU_021176_1_0_1; -.
DR OMA; NMWAVEG; -.
DR OrthoDB; 551774at2759; -.
DR TreeFam; TF329001; -.
DR Proteomes; UP000002277; Chromosome 5.
DR Bgee; ENSPTRG00000017397; Expressed in superior frontal gyrus and 14 other cell types or tissues.
DR GO; GO:0001735; F:prenylcysteine oxidase activity; IBA:GO_Central.
DR GO; GO:0030327; P:prenylated protein catabolic process; IBA:GO_Central.
DR GO; GO:0030328; P:prenylcysteine catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010795; Prenylcys_lyase.
DR InterPro; IPR017046; Prenylcysteine_Oxase.
DR PANTHER; PTHR15944; FARNESYLCYSTEINE LYASE; 1.
DR PANTHER; PTHR15944:SF2; PRENYLCYSTEINE OXIDASE-LIKE; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR Pfam; PF07156; Prenylcys_lyase; 1.
DR PIRSF; PIRSF036292; Prenylcysteine_oxidase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 2: Evidence at transcript level;
KW FAD {ECO:0000256|PIRNR:PIRNR036292};
KW Flavoprotein {ECO:0000256|PIRNR:PIRNR036292};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036292};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..494
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015093028"
FT DOMAIN 120..483
FT /note="Prenylcysteine lyase"
FT /evidence="ECO:0000259|Pfam:PF07156"
SQ SEQUENCE 494 AA; 54646 MW; D5DD8144378BE098 CRC64;
MARAAPLLAA LTALLAAAAA GGDAPPGKIA VVGAGIGGSA VAHFLQQHFG PRVQIDVYEK
GTMGGRLATI SVNKQHYESG AASFHSLSLH MQDFVKLLGL RHRREVVGRS AIFGGEHFVL
EETDWYLLNL FRLWWHYGIS FLRLQMWVEE VMEKFMRIYK YQAHGYAFSG VEELLYSLGE
STFVNMTQHS VAESLLQVGV TQRFIDDVVS AVLRASYGQS AAMPAFAGAM SLAGAQGSLW
SVEGGNKLVC SGLLKLTKAN VIHATVTSVT LHSTEGKALY QVAYENEVGN SSDFYDIVVI
ATPLHLDNSS SNLTFAGFHP PIDDVQGSFQ PTVVSLVHGY LNSSYFGFPD PKLFPFANIL
TTDFPSFFCT LDNICPVNIS ASFRRKQPQE AAVWRVQSPK PLFRTQLKTL FRSYYSVQTA
EWQAHPLYGS RPTLPRFALH DQLFYLNALE WAASSVEVMA VAAKNVALLA YNRWYQDLDK
IDQKDLMHKV KTEL
//
