ID H2QU97_PANTR Unreviewed; 282 AA.
AC H2QU97; A0A2J8KZG3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Transformer 2 alpha homolog {ECO:0000313|EMBL:JAA04286.1, ECO:0000313|Ensembl:ENSPTRP00000032448.2};
GN Name=TRA2A {ECO:0000313|EMBL:JAA04286.1,
GN ECO:0000313|Ensembl:ENSPTRP00000032448.2,
GN ECO:0000313|VGNC:VGNC:10054};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000032448.2, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000032448.2, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA04286.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA04286.1}, Skin
RC {ECO:0000313|EMBL:JAA28886.1}, and Smooth vascular
RC {ECO:0000313|EMBL:JAA12545.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000032448.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC197406; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01007052; JAA04286.1; -; mRNA.
DR EMBL; GABC01007051; JAA04287.1; -; mRNA.
DR EMBL; GABF01009600; JAA12545.1; -; mRNA.
DR EMBL; GABF01009599; JAA12546.1; -; mRNA.
DR EMBL; GABD01004214; JAA28886.1; -; mRNA.
DR RefSeq; XP_001158245.1; XM_001158245.3.
DR RefSeq; XP_016801027.1; XM_016945538.1.
DR STRING; 9598.ENSPTRP00000032448; -.
DR PaxDb; 9598-ENSPTRP00000032448; -.
DR Ensembl; ENSPTRT00000035105.3; ENSPTRP00000032448.2; ENSPTRG00000018988.3.
DR Ensembl; ENSPTRT00000092839.1; ENSPTRP00000078685.1; ENSPTRG00000046098.1.
DR GeneID; 463292; -.
DR KEGG; ptr:463292; -.
DR CTD; 29896; -.
DR VGNC; VGNC:10054; TRA2A.
DR eggNOG; KOG0118; Eukaryota.
DR GeneTree; ENSGT00940000157167; -.
DR HOGENOM; CLU_050438_3_0_1; -.
DR OMA; TNTTQHK; -.
DR OrthoDB; 624416at2759; -.
DR TreeFam; TF106265; -.
DR Proteomes; UP000002277; Chromosome 7.
DR Bgee; ENSPTRG00000018988; Expressed in thymus and 20 other cell types or tissues.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12363; RRM_TRA2; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR48034:SF14; TRANSFORMER-2 PROTEIN HOMOLOG ALPHA; 1.
DR PANTHER; PTHR48034; TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 119..197
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..88
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 282 AA; 32689 MW; EDB5ABE7BEA023FD CRC64;
MSDVEENNFE GRESRSQSKS PTGTPARVKS ESRSGSRSPS RVSKHSESHS RSRSKSRSRS
RRHSHRRYTR SRSHSHSHRR RSRSRSYTPE YRRRRSRSHS PMSNRRRHTG SRANPDPNTC
LGVFGLSLYT TERDLREVFS RYGPLSGVNV VYDQRTGRSR GFAFVYFERI DDSKEAMERA
NGMELDGRRI RVDYSITKRA HTPTPGIYMG RPTHSGGGGG GGGGGGGGGG GRRRDSYYDR
GYDRGYDRYE DYDYRYRRRS PSPYYSRYRS RSRSRSYSPR RY
//
