ID H2R4E9_PANTR Unreviewed; 728 AA.
AC H2R4E9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Muskelin 1 {ECO:0000313|Ensembl:ENSPTRP00000047082.5};
GN Name=MKLN1 {ECO:0000313|Ensembl:ENSPTRP00000047082.5,
GN ECO:0000313|VGNC:VGNC:14046};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000047082.5, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000047082.5, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000047082.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC187616; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC188169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2R4E9; -.
DR Ensembl; ENSPTRT00000046232.5; ENSPTRP00000047082.5; ENSPTRG00000022979.5.
DR VGNC; VGNC:14046; MKLN1.
DR eggNOG; KOG2437; Eukaryota.
DR GeneTree; ENSGT00390000001702; -.
DR HOGENOM; CLU_004210_1_0_1; -.
DR TreeFam; TF323659; -.
DR Proteomes; UP000002277; Chromosome 7.
DR Bgee; ENSPTRG00000022979; Expressed in lymph node and 21 other cell types or tissues.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR010565; Muskelin_N.
DR PANTHER; PTHR15526; MUSKELIN; 1.
DR PANTHER; PTHR15526:SF5; MUSKELIN; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR Pfam; PF13415; Kelch_3; 1.
DR Pfam; PF06588; Muskelin_N; 1.
DR SMART; SM00667; LisH; 1.
DR SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 206..258
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
SQ SEQUENCE 728 AA; 84160 MW; 64539049548EFC84 CRC64;
MAAGGAVAAA PECRLLPYAL HKWSSFSSTY LPENILVDKP NDQSSRWSSE SNYPPQYLIL
KLERPAIVQN ITFGKYEKTH VCNLKKFKVF GGMNEENMTE LLSSGLKNDY NKETFTLKHK
IDEQMFPCRF IKIVPLLSWG PSFNFSIWYV ELSGIDDPDI VQPCLNWYSK YREQEAIRLC
LKHFRQHNYT EAFESLQKKT KIALEHPMLT DIHDKLVLKG DFDACEELIE KAVNDGLFNQ
YISQQEYKPR WSQIIPKSTK GDGEDNRPGM RGGHQMVIDV QTETVYLFGG WDGTQDLADF
WAYSVKENQW TCISRDTEKE NGPSARSCHK MCIDIQRRQI YTLGRYLDSS VRNSKSLKSD
FYRYDIDTNT WMLLSEDTAA DGGPKLVFDH QMCMDSEKHM IYTFGGRILT CNGSVDDSRA
SEPQFSGLFA FNCQCQTWKL LREDSCNAGP EDIQSRIGHC MLFHSKNRCL YVFGGQRSKT
YLNDFFSYDV DSDHVDIISD GTKKDSGMVP MTGFTQRATI DPELNEIHVL SGLSKDKEKR
EENVRNSFWI YDIVRNSWSC VYKNDQAAKD NPTKSLQEEE PCPRFAHQLV YDELHKVHYL
FGGNPGKSCS PKMRLDDFWS LKLCRPSKDY LLRHCKYLIR KHRFEEKAQM DPLSALKYLQ
NDLYITVDHS DPEETKEVKK GGNKFQKLSF SDVDHTYAQR TQLFDTLVNF FPDSMTPPKG
NLVDLITL
//
