ID H2R872_PANTR Unreviewed; 815 AA.
AC H2R872;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Tubulin tyrosine ligase like 13 {ECO:0000313|Ensembl:ENSPTRP00000051272.3};
GN Name=TTLL13 {ECO:0000313|Ensembl:ENSPTRP00000051272.3};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000051272.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000051272.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000051272.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; AACZ04026170; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2R872; -.
DR PaxDb; 9598-ENSPTRP00000051272; -.
DR Ensembl; ENSPTRT00000058301.4; ENSPTRP00000051272.3; ENSPTRG00000007451.7.
DR eggNOG; KOG2158; Eukaryota.
DR GeneTree; ENSGT00940000161367; -.
DR HOGENOM; CLU_010131_7_3_1; -.
DR InParanoid; H2R872; -.
DR OMA; HSWCHLQ; -.
DR TreeFam; TF313087; -.
DR Proteomes; UP000002277; Chromosome 15.
DR Bgee; ENSPTRG00000007451; Expressed in testis and 20 other cell types or tissues.
DR GO; GO:0005929; C:cilium; IBA:GO_Central.
DR GO; GO:0015631; F:tubulin binding; IBA:GO_Central.
DR GO; GO:0070740; F:tubulin-glutamic acid ligase activity; IBA:GO_Central.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR004344; TTL/TTLL_fam.
DR PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR PANTHER; PTHR12241:SF91; TUBULIN POLYGLUTAMYLASE TTLL13; 1.
DR Pfam; PF03133; TTL; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS51221; TTL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT REGION 520..554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 815 AA; 93575 MW; B8D747876B38273C CRC64;
MEPSTCRTME SEEDYVEEKE SEKCVKEGVT NPSNSSQQAL LKADYKALKN GVPSPIMATK
IPKKVIAPVD TGDLEAGRRK RRRKRRSLAI NLTNCKYESV RRAAQMCGLK EVGEDEEWTL
YWTDCAVSLE RVMDMKRFQK INHFPGMTEI CRKDLLARNL NRMYKLYPSE YNIFPRTWCL
PADYGDFQSY GRQRKARTYI CKPDSGCQGR GIFITRNPRE IKPGEHMICQ QYISKPLLID
GFKFDMRVYV LITSCDPLRI FIYEEGLARF ATTPYMEPSL NNLDNVCMHL TNYAINKHNE
NFVRDGAVGS KRKLSTLNIW LQEHSYNPGE LWGDIEDIII KTIISAHSVL RHNYRTCFPQ
YLNGGTCACF EILGFDILLD HKLKPWLLEV NHSPSFTTDS CLDQEVKDAL LCDAMTLVNL
RGCDKRKVME EEKRRVKERL FQCYRQPRES RKEKTESSHV AMLDQERYED SHLGKYRRIY
PGPDTEKYAR FFKHNGSLFQ ETAASKAREE CARQQLEEIR LKQEQQETSG TTRQKARDQN
QGESAGEKSR PRAGLQSLST HLAYRNHNWE KELLPGQLDT MRPQEIVEEE ELERMKALLQ
RETLIRSLGI VEQLTRLQHP GPQGQKKLHE SRDRLGSQEL KSMSLVLLVL LRGAATEQGA
PHFLHPVLPH ESSPRILGAL PSMNAAIPHV PRYHLQPKNF NWTGEPAAIN SCSLSMKKAG
RCYFSSARIR LTSQGQASRR LEAINRVLAG SVPPTLTPKQ GYFLQPERVA SDSWTECTLP
SMVNSEHRAA KVPLCPASAP MLQRSRALLN INQFR
//
