ID H2RCP6_PANTR Unreviewed; 65 AA.
AC H2RCP6; K7BCH8;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Centromere protein X {ECO:0000256|ARBA:ARBA00016388};
GN Name=CENPX {ECO:0000313|Ensembl:ENSPTRP00000057637.3,
GN ECO:0000313|VGNC:VGNC:48942};
GN Synonyms=STRA13 {ECO:0000313|EMBL:JAA11819.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000057637.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000057637.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA11819.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Smooth vascular {ECO:0000313|EMBL:JAA11819.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000057637.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CENP-X/MHF2 family.
CC {ECO:0000256|ARBA:ARBA00009359}.
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DR EMBL; AACZ04066979; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABF01010326; JAA11819.1; -; mRNA.
DR Ensembl; ENSPTRT00000066063.3; ENSPTRP00000057637.3; ENSPTRG00000009783.6.
DR VGNC; VGNC:48942; CENPX.
DR eggNOG; ENOG502S98G; Eukaryota.
DR GeneTree; ENSGT00940000165025; -.
DR HOGENOM; CLU_175684_0_0_1; -.
DR OMA; EDSTICE; -.
DR TreeFam; TF330764; -.
DR Proteomes; UP000002277; Chromosome 17.
DR Bgee; ENSPTRG00000009783; Expressed in cerebellar cortex and 21 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0051382; P:kinetochore assembly; IEA:InterPro.
DR Gene3D; 1.20.5.4980; -; 1.
DR Gene3D; 6.10.130.30; -; 1.
DR InterPro; IPR018552; CENP-X.
DR PANTHER; PTHR28680; CENTROMERE PROTEIN X; 1.
DR PANTHER; PTHR28680:SF1; CENTROMERE PROTEIN X; 1.
DR Pfam; PF09415; CENP-X; 1.
PE 2: Evidence at transcript level;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
SQ SEQUENCE 65 AA; 7145 MW; C588A98FE4F782DF CRC64;
MEGAGAGSGF RKELVSRLLH LHFKDDKTKG AEAAVRGVRQ AQAEDALRVD VDQLEKVLPQ
LLLDF
//
