ID H2S6I9_TAKRU Unreviewed; 396 AA.
AC H2S6I9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Thioredoxin-interacting protein {ECO:0000256|ARBA:ARBA00039479};
GN Name=txnip {ECO:0000313|Ensembl:ENSTRUP00000008011.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000008011.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000008011.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000008011.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the arrestin family.
CC {ECO:0000256|ARBA:ARBA00005298}.
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DR RefSeq; XP_003977733.1; XM_003977684.2.
DR AlphaFoldDB; H2S6I9; -.
DR STRING; 31033.ENSTRUP00000008011; -.
DR Ensembl; ENSTRUT00000008059.3; ENSTRUP00000008011.3; ENSTRUG00000003416.3.
DR GeneID; 101071854; -.
DR KEGG; tru:101071854; -.
DR CTD; 368359; -.
DR eggNOG; KOG3780; Eukaryota.
DR GeneTree; ENSGT00940000158522; -.
DR HOGENOM; CLU_039221_1_1_1; -.
DR InParanoid; H2S6I9; -.
DR OMA; GPQQCKQ; -.
DR OrthoDB; 22053at2759; -.
DR TreeFam; TF313650; -.
DR Proteomes; UP000005226; Chromosome 12.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.640; -; 2.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR11188; ARRESTIN DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11188:SF14; THIOREDOXIN-INTERACTING PROTEIN; 1.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; E set domains; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 177..304
FT /note="Arrestin C-terminal-like"
FT /evidence="ECO:0000259|SMART:SM01017"
SQ SEQUENCE 396 AA; 44008 MW; C234CA7766DA2B85 CRC64;
MVAMTKRLKT FQVVFTDPTK TFFCGGDVVS GRVQVEVSEA TRVSAVRLLA LGCAKVEYAK
GKQRCRQEAE YLRHEEVLRL DSQPTDSDGS VVLRPGNKYE YTFGFELPQN GQLVSTYKGK
FGYVHYYVKA LLERPQQPTL ECKKSFDVEE PLDVNTPDLL SPTGGMKEKK VTCMFIPDGQ
VSLNAKIDRS GFCEGEDICI NAKFENTCSR IVVPKAAIIA KQIYQANGRT KVFRQKLSSV
RGNHIISGMC DAWQGKTIRV PKIKPSMLGS NIIRVEYALM IYIHIPGSEK LILELPLVIG
TAGLGSRSNS VSSQEGSVSN ASQSWVSLRM PSEPPSYCDI TRDCRLDQPL TPLLDDFDGE
DSPIFMNVPA FQYPPLPAYA ESEEEHSAHA RMLPVC
//
