ID H2SJP4_TAKRU Unreviewed; 1148 AA.
AC H2SJP4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Tudor domain-containing protein 7B-like {ECO:0000313|Ensembl:ENSTRUP00000012627.2};
GN Name=LOC101066426 {ECO:0000313|Ensembl:ENSTRUP00000012627.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000012627.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000012627.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000012627.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_011604897.1; XM_011606595.1.
DR RefSeq; XP_011604898.1; XM_011606596.1.
DR RefSeq; XP_011604899.1; XM_011606597.1.
DR AlphaFoldDB; H2SJP4; -.
DR STRING; 31033.ENSTRUP00000012627; -.
DR Ensembl; ENSTRUT00000012688.3; ENSTRUP00000012627.2; ENSTRUG00000005266.3.
DR GeneID; 101066426; -.
DR KEGG; tru:101066426; -.
DR CTD; 100004703; -.
DR GeneTree; ENSGT00890000139482; -.
DR InParanoid; H2SJP4; -.
DR OMA; YVAKVEN; -.
DR OrthoDB; 5403690at2759; -.
DR Proteomes; UP000005226; Chromosome 8.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd09973; LOTUS_2_TDRD7; 1.
DR CDD; cd09974; LOTUS_3_TDRD7; 1.
DR CDD; cd20428; Tudor_TDRD7_rpt2; 1.
DR CDD; cd20429; Tudor_TDRD7_rpt3; 1.
DR Gene3D; 2.30.30.140; -; 3.
DR Gene3D; 2.40.50.90; -; 3.
DR Gene3D; 3.30.420.610; LOTUS domain-like; 3.
DR InterPro; IPR041966; LOTUS-like.
DR InterPro; IPR025605; OST-HTH/LOTUS_dom.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR037978; TDRD7_LOTUS_3.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047448; Tudor_TDRD7_rpt2.
DR InterPro; IPR047449; Tudor_TDRD7_rpt3.
DR PANTHER; PTHR22948:SF75; FI20010P1; 1.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF12872; OST-HTH; 1.
DR Pfam; PF00567; TUDOR; 3.
DR SMART; SM00333; TUDOR; 3.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 3.
DR PROSITE; PS51644; HTH_OST; 3.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 3..76
FT /note="HTH OST-type"
FT /evidence="ECO:0000259|PROSITE:PS51644"
FT DOMAIN 228..298
FT /note="HTH OST-type"
FT /evidence="ECO:0000259|PROSITE:PS51644"
FT DOMAIN 367..437
FT /note="HTH OST-type"
FT /evidence="ECO:0000259|PROSITE:PS51644"
FT DOMAIN 536..594
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 117..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 876..956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..918
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..944
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1148 AA; 128020 MW; D381A384FDB3DE7A CRC64;
MADVELVKKM LRAVLQTNKG RISLPRLQSE YKELTGEQIP HKQMGYNQLD ALLASMPSLV
HMERNRSGET VCFLSSTNER AHVAKVVARQ RSSKKTGRPH LVNTQMRVKP VTPLVLNAKP
QTFLRQPNYR GRGGGRGGGR AAGHGEFRQT RDIRDAPSEG KAGLHLNKTP NTANRKGNPP
ADKPEKRMTL PSRFQKEVHA HLSRNAQPTS SLPNLNESHS SDKGRPYNRQ QVQGRIREIL
GKYSNGFWVS KLPQIYRELY KQDLPTEAIK DLETWTHICI VEKTCNSNPS ELLLYPARDQ
SAPLSPLPPG SSSAVISTSH VTADKSSNSP TQQKTPSMQL TRSGSRSSRS PPSSSSSPSP
PSSPATLSSD LKLKLEELLE KYSNGLWAHA LPKLFQDTYK TKLPKHVLEN LHLLNDFCTV
DYPMPDNPKR AILYRRSSST GGGGGEDENC NRRNSSISEE ELRVRQELGR RLSNHAVPAL
QIPKEEYPSV LVVEATNTNA VVLRYIGEGY SRAQESMEDE MREFYGSGRS NPPLMSPSSG
QLVAIRAEEE EEILRAQVCE VMDEKVKVHY VDHGFSEVIS KTKVFELHEK FFQLPFQASK
CKLAGLEPFC QEPEVLKKFE TIASGKILLA EILERGQIPL VVLYDTSQDD DLNINAACMK
TLQDKTLSSP LQVNSAYMNV TISSVCSDGT IYCQLPSRGL AKLNDVLEKV ETYFHSQVTS
EFLVSRPFCG KGCLARYKGK WSRVEITNLH GSRVLDILFI DVGVQASVEV FELREIPSPF
LRDLMAIPPQ AVKCCLADLA VSVGSWTPEA VQWLRDKVLN TTDCSIKVAK VDDTRRCVSV
HFFTDKNFHD STRSLNRQMA QSNLLKQQPD VFLTSHSPAK ISTPSSSSKT FSSANSTNGS
PALSSSSSSS SSSAKPTIRR ALSGPRDASG GNRSNSSPSD SPSSPTSSPH LPPLMELPTA
GNNMDVYISV ACHPGHFVLQ PWRDMYKLVV LMGEMILYYN KTEEKPLNIE KNQIYAAKVE
NNWHRVLVKG VLNNGLVSAY ELDYGKHELV SCTQFRPLIK EFRQLPFQAI TAQLAGLKPR
QWSEEASIVF RNHVEKKPLV AQLEATQEAT YPWDRKLTVF LVDTSQEEKD IWVHDIMAEF
ADELTNEL
//
