ID H2SRT0_TAKRU Unreviewed; 586 AA.
AC H2SRT0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Solute carrier family 23 member 1-like {ECO:0000313|Ensembl:ENSTRUP00000015117.3};
GN Name=LOC101076958 {ECO:0000313|Ensembl:ENSTRUP00000015117.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000015117.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000015117.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000015117.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2SRT0; -.
DR STRING; 31033.ENSTRUP00000083853; -.
DR Ensembl; ENSTRUT00000015186.3; ENSTRUP00000015117.3; ENSTRUG00000006210.3.
DR GeneTree; ENSGT00950000182953; -.
DR HOGENOM; CLU_017959_5_4_1; -.
DR Proteomes; UP000005226; Chromosome 9.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR PANTHER; PTHR11119:SF22; SOLUTE CARRIER FAMILY 23 MEMBER 4; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 43..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 586 AA; 63626 MW; F578E0F4EBCEE0E1 CRC64;
LNQTVCLEGH FCDLSDTKDV EDVGTSLEGD ANKLAYCVTD VPPWYLCIFL GIQHCLTAFG
GIIAIPIILS QGLCLQHDAL TQSHLISTIF FVSGICTLLQ VVFGVRLPIL QGGTFTLLAP
SMAMLSMPEW TCPAWTHNAS LVNTTSPEFT EVWQTRMRAL QGSFIMGSLF QMFVGFSGLI
GHFMRFIGPL TIAPTISLIG LSLFDSAGTS AGYHWGVAVM TTALITLFSQ YLRHIPVPIP
AYSIHKKLQF TRVLLGIVFS WLICYILTAY DVLPTDPENY GYLARTDLKK DVISKAPWIT
FPYPCQWGMP TVSLAGAVGI LAGVISSMIE SVGDYHACAR LSGAPPPPKH AINRGIGMEG
LGCLLAGAWG TGNGTTSYSE NVGALGITKV GSRMVILFSG VLMVVMGMMG KVAAIFTTIP
EPVMGGMFLV MFGVISAAGV SNLQYVNMNS SRNIFVFGFS MFSALVIPNW ILKHPEAIST
GLVELDQVLQ VLLTTSMFVG GFIGFILDNT IPGSKHERGI LAWNEAHEGD FSNTLESREV
YNLPFGISTY FSSFPWLRHI PFCPPGPCTN SQTTLSTYNV GVHWWS
//
