ID H2T7P6_TAKRU Unreviewed; 395 AA.
AC H2T7P6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Speckle type BTB/POZ protein like {ECO:0000313|Ensembl:ENSTRUP00000020686.3};
GN Name=spopl {ECO:0000313|Ensembl:ENSTRUP00000020686.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000020686.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000020686.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000020686.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the Tdpoz family.
CC {ECO:0000256|ARBA:ARBA00010846}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_011609923.1; XM_011611621.1.
DR AlphaFoldDB; H2T7P6; -.
DR STRING; 31033.ENSTRUP00000020686; -.
DR Ensembl; ENSTRUT00000020772.3; ENSTRUP00000020686.3; ENSTRUG00000008272.3.
DR eggNOG; KOG1987; Eukaryota.
DR GeneTree; ENSGT00940000155953; -.
DR HOGENOM; CLU_004253_2_0_1; -.
DR InParanoid; H2T7P6; -.
DR OMA; LCTFTVM; -.
DR TreeFam; TF313419; -.
DR Proteomes; UP000005226; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030163; P:protein catabolic process; IEA:UniProt.
DR CDD; cd18519; BACK_SPOPL; 1.
DR Gene3D; 6.10.250.3030; -; 1.
DR Gene3D; 6.20.250.50; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR008974; TRAF-like.
DR PANTHER; PTHR24413; SPECKLE-TYPE POZ PROTEIN; 1.
DR PANTHER; PTHR24413:SF91; SPECKLE-TYPE POZ PROTEIN-LIKE; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00917; MATH; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50144; MATH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 31..161
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT DOMAIN 200..270
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 395 AA; 44968 MW; 167E55451033EFFC CRC64;
MSRVPTPPPN GEMASGPVAE SWCYTQVKVV KFSYMWTINN FSFCREEMGE VLKSSTFSSG
PNDKMKWCLR VNPKGLDDES KDYLSLYLLL VSCPKSEVRA KFKFSLLNAK REETKAMESQ
RAYRFVQGKD WGFKKFIRRD FLLDEANGLL PDDKLTLFCE VSVVQDSVNI SGQSNMNMLK
VPECQLSDDL GSLWEQSRFT DCSLWVRGQE FKAHRAILAA RSPVFKAMFE HEMKDTKKFF
QNRVDIADIE PDVFKEMMRF VYTGRAPNLE KMADNLLAAA DKYALKRLKV MCEEALCNSL
SVENVADTLI LADLHSAEQL KAQAIDFINR CSVLRQLGCK DGKNWNSNHA TDIMETAGWK
SMIQSHPHLV AEAFRALASA QCPPFGPPRK RLKQS
//
