ID   H2TFH1_TAKRU            Unreviewed;       462 AA.
AC   H2TFH1;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 3.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Motile sperm domain containing 2 {ECO:0000313|Ensembl:ENSTRUP00000023417.3};
GN   Name=mospd2 {ECO:0000313|Ensembl:ENSTRUP00000023417.3};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000023417.3, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000023417.3, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000023417.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; H2TFH1; -.
DR   Ensembl; ENSTRUT00000023514.3; ENSTRUP00000023417.3; ENSTRUG00000009311.3.
DR   GeneTree; ENSGT00390000016713; -.
DR   HOGENOM; CLU_028924_1_0_1; -.
DR   Proteomes; UP000005226; Chromosome 1.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000535; MSP_dom.
DR   InterPro; IPR008962; PapD-like_sf.
DR   PANTHER; PTHR46384; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR46384:SF1; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF00650; CRAL_TRIO; 1.
DR   Pfam; PF00635; Motile_Sperm; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR   SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR   SUPFAM; SSF49354; PapD-like; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
DR   PROSITE; PS50202; MSP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT   DOMAIN          84..226
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000259|PROSITE:PS50191"
FT   DOMAIN          310..424
FT                   /note="MSP"
FT                   /evidence="ECO:0000259|PROSITE:PS50202"
FT   REGION          242..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        248..265
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   462 AA;  52300 MW;  6D39EB2C3BF125BF CRC64;
     SRELQRFTNE FLQDSTEKYD SRDVERLQSE DALVEGYLTW RLYVVDDALK MIDESLQWRK
     EFGVNDLTES VIPRWMFETG AVFLHGYDKE GNKLFWFKVK LHVKDPKTVL DKKKYVAFWL
     ERYAKKEPGM PLTVVFDMSD SGISNIDMDF VRYIINCFKV YYPKFLSKMI IVDMPWIMNA
     AWKIVKTWLG PEAISKLRFA SKSEVQTFIG PEYLPAHMGG TDPFKYSYPP LPDDDFQMPL
     CDNGPVASED EMESKEADAE SKDALESSFS SEVAVNFLED SLRSEDNDKG ETSTKYKGAR
     KPLTTFKGHL LHVSPAEELS FGSVETERKS LIILSNVAKN QVAFKVRTTA PEKYRVKPSS
     SCCEPGASVD IVVSLHGGSQ ASPQDRFLIM AAEMENAGSQ ELALFWKEVP KAKVMEHRLR
     CHVLEGAKPT GTPLRDAPVE MATSGQQELS MVVSSGGRRT CS
//