ID H2TQN3_TAKRU Unreviewed; 316 AA.
AC H2TQN3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Matrilin 2 {ECO:0000313|Ensembl:ENSTRUP00000026990.3};
GN Name=MATN2 {ECO:0000313|Ensembl:ENSTRUP00000026990.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000026990.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000026990.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000026990.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2TQN3; -.
DR Ensembl; ENSTRUT00000027099.3; ENSTRUP00000026990.3; ENSTRUG00000010697.3.
DR GeneTree; ENSGT00940000158008; -.
DR Proteomes; UP000005226; Chromosome 7.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF35; MATRILIN-2; 1.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..316
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025527167"
FT DOMAIN 46..225
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 287..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 316 AA; 34746 MW; 5AB0CD11ECB30B82 CRC64;
MKPLALVLLS LLFCLSQAGV NKHRPRSAAA RGQNETTNPC KAVPLDFVFV IDSSRSIRPN
DYEKVKTFIV NLIQFLEIGP DATRVGLLQY GSVVQPEFSL NTFTSKAEVE QAVRNMRHLA
TGTMTGLAIK YAMETSFTEE DGARAAHLHI PRIAVIVTDG RPQDTVEQVA AQARQAGIQI
FAIGVGRVDM NTLKTIGSEP HSEHVHLVAN FSQIETLISV FHSKLCGGSE TCELVDHQCQ
HTCVSSPASY RCKCREGFIL NPDGKTNHLY SCVCRCRAGF TLRPDGRTCQ SESDRPPHHG
GRVLYQMGGR RQSVPT
//
