ID H2TUY2_TAKRU Unreviewed; 607 AA.
AC H2TUY2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Dachshund homolog 1-like {ECO:0000313|Ensembl:ENSTRUP00000028491.2};
GN Name=LOC101073951 {ECO:0000313|Ensembl:ENSTRUP00000028491.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000028491.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000028491.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000028491.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DACH/dachshund family.
CC {ECO:0000256|ARBA:ARBA00038192}.
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DR RefSeq; XP_011605195.1; XM_011606893.1.
DR AlphaFoldDB; H2TUY2; -.
DR Ensembl; ENSTRUT00000028605.3; ENSTRUP00000028491.2; ENSTRUG00000011286.3.
DR GeneTree; ENSGT00390000001134; -.
DR Proteomes; UP000005226; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd21081; DHD_Dac; 1.
DR Gene3D; 3.10.260.20; Ski; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR003380; SKI/SNO/DAC.
DR InterPro; IPR037000; Ski_DNA-bd_sf.
DR PANTHER; PTHR12577; DACHSHUND; 1.
DR PANTHER; PTHR12577:SF14; DACHSHUND HOMOLOG 1; 1.
DR Pfam; PF02437; Ski_Sno; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 77..182
FT /note="SKI/SNO/DAC"
FT /evidence="ECO:0000259|Pfam:PF02437"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..24
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..594
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 65530 MW; CBD3131FDC5A4B8E CRC64;
MAVPAALIPP SPLVPPPPIS TPSATTSPPS TTSSPSPSLA PPSGPGQTLF RSELLATSSP
GIPTAALPPS KPVYSTPSPV ENIPQNNECK MVELRGAKVA SFTVDGCELI CLPQAFDLFL
KHLVGGLHTV YTKLKRLEIT PVVCNVEQVR ILRGLGAIQP GVNRCKLISR KDFETLYNDC
TNASSRPGRP PKRTQSVTSP ENPHIMPHSV PGLMSPGMIP PTGLTAAAAA AANAAIAEAM
KVKKIKLEAM SSYHSNANHH GGDGENGDLS SSVGLELPFM MMPHPLIPVS LPPASVTMAM
SQMNHLSTIA NMAAAAQGQS LPSRMVTSVI KGLQERVPDS PSPAPSLEDH RRPGSHPSSH
RSSSVSSSPA HTESSSDRIP IHHNGLSMNH ALLGLSPNIP PGPKEGDLAH DMSHEAATHK
RIHADKEETS VCTPTARDSY ERLSLAGQAL PPGFPSPFLF PDGLSSIETL LTNIQGLLKV
AIDNARAQEK QVQLEKTELK MELFRERELR ETLEKQLAME QKNRAIIQKR LKKEKKAKRK
LQEALEYESK RREQVEQTLK QPSPSDSMRS LNDSLTPEME SDRSSGRTDA ERTIQDGRLF
LKTTVMY
//
