ID H2U504_TAKRU Unreviewed; 589 AA.
AC H2U504;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Ectoderm-neural cortex protein 1-like {ECO:0000313|Ensembl:ENSTRUP00000032017.1};
GN Name=LOC101061670 {ECO:0000313|Ensembl:ENSTRUP00000032017.1};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000032017.1, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000032017.1, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000032017.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_003974251.1; XM_003974202.2.
DR AlphaFoldDB; H2U504; -.
DR STRING; 31033.ENSTRUP00000032017; -.
DR Ensembl; ENSTRUT00000032140.3; ENSTRUP00000032017.1; ENSTRUG00000012650.3.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00950000182983; -.
DR HOGENOM; CLU_004253_14_6_1; -.
DR InParanoid; H2U504; -.
DR OMA; PQSNKWT; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF329218; -.
DR Proteomes; UP000005226; Chromosome 20.
DR GO; GO:0061371; P:determination of heart left/right asymmetry; IEA:Ensembl.
DR GO; GO:0071910; P:determination of liver left/right asymmetry; IEA:Ensembl.
DR CDD; cd18464; BACK_KLHL25_like; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF488; KELCH-LIKE PROTEIN 20; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 46..114
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 589 AA; 65870 MW; C70A13ED2E65BB23 CRC64;
MSFSNHENRK SRSSSGSMNI QLFHKTSHAD SLLTQLNLLR KRKVFTDVVL KAGNRSFPCH
RAVLASCSRY FEAMFSGGLR ESRDADVNFH DSLHPEVLEL LLDYAYSARV IINEENAESL
LEAGDMLQFH DIRDAAAEFL EKNLHQSNCL GMMLLSDAHQ CQRLYELSWR MCLANFDTLF
KTEDFLSLPK DKVQELILSE ELEVEDESLV YEAVIDWVRA DMERRHGELP DLLRCVRLAL
LPETYLLKNV ASEELVMCHK VGREIVEDAV RCKMRILQND GIVTGFCARP RKVSQALLLL
GGQTFMCDKI YMIDNKTKEI TPKTDIPSPR KECSACAIGC KVYVTGGRGS ENGASKDVWV
YDTLHDEWSK AAPMLVARFG HGSAELDHML FVVGGHTSLT GSFPASPSVS LKQVEQYDPQ
TNKWTLVAPL REGVSNAAVV GAKNKLFAFG GTSVNRDKYP KVQCFDPCQN RWSVPAACPQ
LWRYTAAAVV GNHVVVIGGD TEFSASSAYR FNSETYQWSK FADVTAKRIS CHAVASGNRL
YVVGGYFGAQ RCKTLDCYDP ASDSWDSVTS VPYSLIPTAF VSTWKYLSA
//
