ID H2U7M2_TAKRU Unreviewed; 328 AA.
AC H2U7M2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Carbonic anhydrase-related protein 10-like {ECO:0000313|Ensembl:ENSTRUP00000032938.3};
GN Name=CA10 {ECO:0000313|Ensembl:ENSTRUP00000032938.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000032938.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000032938.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000032938.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Does not have a catalytic activity.
CC {ECO:0000256|ARBA:ARBA00002258}.
CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC {ECO:0000256|ARBA:ARBA00010718}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_003964317.1; XM_003964268.1.
DR AlphaFoldDB; H2U7M2; -.
DR STRING; 31033.ENSTRUP00000032938; -.
DR Ensembl; ENSTRUT00000033063.3; ENSTRUP00000032938.3; ENSTRUG00000012987.3.
DR GeneID; 101075224; -.
DR KEGG; tru:101075224; -.
DR CTD; 568543; -.
DR eggNOG; KOG0382; Eukaryota.
DR GeneTree; ENSGT00940000155223; -.
DR HOGENOM; CLU_039326_7_1_1; -.
DR InParanoid; H2U7M2; -.
DR OMA; QMPRIRI; -.
DR OrthoDB; 49814at2759; -.
DR TreeFam; TF352926; -.
DR Proteomes; UP000005226; Chromosome 5.
DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd03121; alpha_CARP_X_XI_like; 1.
DR Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR InterPro; IPR041878; Alpha_CARP_X/XI.
DR InterPro; IPR001148; CA_dom.
DR InterPro; IPR036398; CA_dom_sf.
DR InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR PANTHER; PTHR18952:SF138; CARBONIC ANHYDRASE-RELATED PROTEIN 10; 1.
DR Pfam; PF00194; Carb_anhydrase; 1.
DR SMART; SM01057; Carb_anhydrase; 1.
DR SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR PROSITE; PS51144; ALPHA_CA_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..328
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025358717"
FT DOMAIN 31..301
FT /note="Alpha-carbonic anhydrase"
FT /evidence="ECO:0000259|PROSITE:PS51144"
SQ SEQUENCE 328 AA; 37387 MW; 5BB5F59BD32CF9B0 CRC64;
MPNVWDIAVV LQTFIICTSS AQPIASKLDD SWWAYKDVVQ GSFVPVPSFW GLVHSAWNLC
AIGKRQSPIN IETSHMIFDP YLTPLKLNTG GRKMGGTMYN TGKHVSLRPD KAHLVNISGG
PLGYSYRLEE VRLHFGSEDS QGSEHLLNGQ GFPGEVQLIH YNQDLYANYS EAAKSPHGIA
VVSIFIKLSE NSNSFLNRML NRDTITRINY RHDAFLLMGL NIADLYPDTT RYITYEGSIT
IPPCYETSTW ILINKPVYVT QMQMHSLRLL SQNEPYKIFL SMSDNIRPTQ PLLQRCIRTN
INFSKQGRNC PNNRALRPQY RVNQWLLK
//
