ID H2UUK0_TAKRU Unreviewed; 502 AA.
AC H2UUK0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Tripartite motif-containing protein 35-like {ECO:0000313|Ensembl:ENSTRUP00000040625.3};
GN Name=LOC101078109 {ECO:0000313|Ensembl:ENSTRUP00000040625.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000040625.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000040625.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000040625.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRIM/RBCC family.
CC {ECO:0000256|ARBA:ARBA00008518}.
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DR AlphaFoldDB; H2UUK0; -.
DR Ensembl; ENSTRUT00000040767.3; ENSTRUP00000040625.3; ENSTRUG00000015891.3.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT01030000234583; -.
DR OrthoDB; 5479648at2759; -.
DR TreeFam; TF334286; -.
DR Proteomes; UP000005226; Chromosome 18.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd12893; SPRY_PRY_TRIM35; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF611; E3 UBIQUITIN-PROTEIN LIGASE TRIM39-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..502
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030172452"
FT DOMAIN 38..78
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 116..157
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 304..496
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 346..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 57130 MW; DEB13D03117FB178 CRC64;
MTFHNRKQEA ILFVLFQQLF AETAFRMAGR LPEADLSCSI CCEVFRDPVV LKCSHSFCSP
CLQQYWSIRT NRDCPLCRRQ SLDDPVPSLT LKNLCESYLE ENDDMVGKKA EEPCGDPEEM
CPIHGEKFKL FCTKDNEPIC VVCHTSRKHK QHECFPVSEA VADVRGKMTS ALSSLQDKKE
AFEKTKKNYE NAAAYIQVQA RFVETQTHAE FEKLHSFLRA EEETRMQALK REEEQRSRAM
AEKIQEITKD ITSVSECIQA LEGDLALDGI SVLHNCKKTL ARAAVPIQDP VMHPGALIDV
AKYVGSLSFH VWDKMQKLVK YTPVTLDPNT AAPWLVLSDD LTSVSDSKEK RKLPNNPERY
DPDTGVLGRE GFTTGKHAWD VSVGDNTAWV VGVAKASVTR KKKVSSVLKN GYLCIYFYHK
MYFAGTSPLT RLNLRRNPEK VRVQLDCDRS RVSFYDLQDN THIYTFKHAI AERVFPYFWV
GCQQCPLTIQ PLDVSVVANE VF
//
