ID H2VAB7_TAKRU Unreviewed; 262 AA.
AC H2VAB7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000046158.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000046158.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000046158.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2VAB7; -.
DR STRING; 31033.ENSTRUP00000046158; -.
DR Ensembl; ENSTRUT00000046313.3; ENSTRUP00000046158.3; ENSTRUG00000018016.3.
DR eggNOG; KOG2710; Eukaryota.
DR GeneTree; ENSGT00940000155312; -.
DR HOGENOM; CLU_048582_0_0_1; -.
DR InParanoid; H2VAB7; -.
DR OMA; MDSMEFL; -.
DR TreeFam; TF342052; -.
DR Proteomes; UP000005226; Chromosome 16.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR042869; ARHGAP11A/B.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15670; RHO GTPASE ACTIVATING PROTEIN 11A; 1.
DR PANTHER; PTHR15670:SF4; RHO GTPASE-ACTIVATING PROTEIN 11A; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 41..224
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 262 AA; 29329 MW; 289A45D13CF02843 CRC64;
MKVTDSSVIR FHLQVLHGIT VKSIEGRKDR LFISGAKIFG VPLENLPRRY IPEFGLVPCF
LVDACSFLLE RAATVGLFRK PGSLPRIKTL NNGETCLSTA LPYDVATLIK QFCRELPEPL
FPTELHTALL KAQALPNAKD KTSALQLLSC LLPARNSSCL HYLFNFLSRV SQRCAENLMT
SSNLATVFAP CLLPPPSKAE MSESRLELRV LVLHAFIENP HLFGNDINPH LILLLSCIRP
ARRVCICQAS SLKMSWTAWN FW
//
