ID H2ZWV1_LATCH Unreviewed; 443 AA.
AC H2ZWV1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000001872.1};
GN Name=BAAT {ECO:0000313|Ensembl:ENSLACP00000001872.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000001872.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000001872.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC {ECO:0000256|ARBA:ARBA00006538}.
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DR EMBL; AFYH01259227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01259228; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01259229; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01259230; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01259231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01259232; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01259233; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01259234; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01259235; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2ZWV1; -.
DR Ensembl; ENSLACT00000001885.1; ENSLACP00000001872.1; ENSLACG00000001670.2.
DR GeneTree; ENSGT01010000222336; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000001670; Expressed in muscle tissue and 6 other cell types or tissues.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR InterPro; IPR014940; BAAT_C.
DR InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR PANTHER; PTHR10824:SF1; ACYL-COENZYME A AMINO ACID N-ACYLTRANSFERASE 1-RELATED; 1.
DR PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR Pfam; PF08840; BAAT_C; 1.
DR Pfam; PF04775; Bile_Hydr_Trans; 1.
DR PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..443
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003578776"
FT DOMAIN 37..166
FT /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT acid N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04775"
FT DOMAIN 228..436
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
FT ACT_SITE 257
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 351
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 385
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ SEQUENCE 443 AA; 49116 MW; 7EF1646E40906299 CRC64;
ALSPRVSNPG TRGGVFLLCL LPAMVVLTVA PEISLSDEPV TIRVSSLKPS QLVTLMTSLT
DEKGVKFLSR AFYRADENGD VDLQKAASLG GNYTGVEPMG LFWSLKPEKP FHRLMKREVM
ETPFYVKVEV FDKYVLMENP EVEAAAAVTL ERWFRSPGVR RIPIREGRVR GALFLPPGDG
PFPGVIDMFG GAGGLIEFRS SLLASRGFAA LALAYFAYED LPIFVKKIEL EYFEEAAEIL
QKHPKVKANG IGVIGVSLGA QIALAMATFL KQVVTTVCIS GSSAIYGVDI HYRSLIIRGI
PHINEKIRVL EHNIMQSYHA FAEPRDEAYR DCIFPCERAQ GHILFIVGED DQCLDSKLLY
GEAIRRMKQH GKTNWAMLAY PGAGHLIEPP CSPFCSVSRN RTSKLPLLWG GEGSAHGRAQ
KHSWKEIQSF FQQHVGQWEH SGL
//
