ID H2ZXX0_LATCH Unreviewed; 413 AA.
AC H2ZXX0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Arrestin, beta 2a {ECO:0000313|Ensembl:ENSLACP00000002241.1};
GN Name=ARRB2 {ECO:0000313|Ensembl:ENSLACP00000002241.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000002241.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000002241.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the arrestin family.
CC {ECO:0000256|ARBA:ARBA00005298}.
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DR EMBL; AFYH01239988; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01239989; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01239990; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01239991; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01239992; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01239993; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01239994; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01239995; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01239996; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01239997; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2ZXX0; -.
DR STRING; 7897.ENSLACP00000002241; -.
DR Ensembl; ENSLACT00000002259.1; ENSLACP00000002241.1; ENSLACG00000002001.2.
DR eggNOG; KOG3865; Eukaryota.
DR GeneTree; ENSGT00950000182887; -.
DR HOGENOM; CLU_033484_1_1_1; -.
DR InParanoid; H2ZXX0; -.
DR OMA; EADHQVS; -.
DR TreeFam; TF314260; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000002001; Expressed in chordate pharynx and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.640; -; 1.
DR Gene3D; 2.60.40.840; -; 1.
DR InterPro; IPR000698; Arrestin.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR017864; Arrestin_CS.
DR InterPro; IPR014753; Arrestin_N.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR11792; ARRESTIN; 1.
DR PANTHER; PTHR11792:SF20; BETA-ARRESTIN-2; 1.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR PRINTS; PR00309; ARRESTIN.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; E set domains; 2.
DR PROSITE; PS00295; ARRESTINS; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 194..352
FT /note="Arrestin C-terminal-like"
FT /evidence="ECO:0000259|SMART:SM01017"
SQ SEQUENCE 413 AA; 46994 MW; 587EA9C920B49EA0 CRC64;
STRKPTKFGL LEIGPQRRLT VYLGKRDFVD HLDHVDPVDG VVLLDPEYLK DRKVFVTLTC
AFRYGREDLD VLGLSFRKDL FIATFQAFPP LPEEKKPLTR LQERLIKKLG QNAYPFFFTI
PQNLPCSVTL QPGPEDTGKA CGVDFEVRAF CAKTMEEKIH KRNSVRLVIR KVQYAPEKPG
PQPMAETTRH FLMSDRSLHL EASLDKELYY HGEPISVNVH VTNNSTKTVK KIKISVRQYA
DICLFSTAQY KCPVAQLEQD DQVSPSSTFC KVYTLIPLLT NNREKRGLAL DGKLKHEDTN
LASSTIVKEG ANKEVLGILV SYRVKVKLVV SRGGSVLHPS RNNSTVIYQE YNECTRPQLV
LAYPVPESDT PVDANLIEFE TNFGQDDDIV FEDFARLRLK GLKDDKEEDD YFC
//
