ID H2ZZF7_LATCH Unreviewed; 1172 AA.
AC H2ZZF7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=WWC family member 3 {ECO:0000313|Ensembl:ENSLACP00000002778.1};
GN Name=WWC3 {ECO:0000313|Ensembl:ENSLACP00000002778.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000002778.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000002778.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01091433; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091434; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091435; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091436; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091437; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091438; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091439; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091440; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091441; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01091442; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005998281.1; XM_005998219.2.
DR AlphaFoldDB; H2ZZF7; -.
DR STRING; 7897.ENSLACP00000002778; -.
DR Ensembl; ENSLACT00000002800.1; ENSLACP00000002778.1; ENSLACG00000002484.1.
DR GeneID; 102350265; -.
DR KEGG; lcm:102350265; -.
DR CTD; 55841; -.
DR eggNOG; KOG3209; Eukaryota.
DR GeneTree; ENSGT00410000025556; -.
DR HOGENOM; CLU_005420_0_0_1; -.
DR InParanoid; H2ZZF7; -.
DR OMA; HSGFHKQ; -.
DR OrthoDB; 1334597at2759; -.
DR TreeFam; TF324040; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000002484; Expressed in pelvic fin and 6 other cell types or tissues.
DR CDD; cd08680; C2_Kibra; 1.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037771; C2_WWC.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR14791; BOMB/KIRA PROTEINS; 1.
DR PANTHER; PTHR14791:SF25; PROTEIN WWC3; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 15..48
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 62..95
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 683..806
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 442..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 880..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 942..979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 116..200
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 311..397
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 586..605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 880..894
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..973
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1172 AA; 133076 MW; 78541C3B52612109 CRC64;
MTGVSSSWRR ESSELPLPSG WEEARDYDGR VFYIDHNTRQ TSWIDPRDRI TKPLTFADCV
GSELPLGWEV VYDQQIGVYY IDHINQITQI EDPRAQWRRE QERMLKEYLV VAQEALNAKK
EIYQIKQQRL ELAQAEYQQL HEMCEEDSRS HTSSYSGSSS NTKYDLDQIK AEIASRRERL
SRLKRELAQM KQELQYKEKG VETLQEIDRK MSNNQNSYKL DEAQAIMNEL RTIKKAISTG
EKERQDLIQS LAKLTDGFQN SCCITHSLQD FRNNFGSLSD SCLPQQYCDA ESQTDIIGEF
GHDERTRLAD KMKLNWQYEE AKKRVSSLQH QLAQMDNETW PGMAEADRDR LQVIKEKEAL
LQELQLISQQ RRSPDDIVRL EAEKRRLEEE IQRARSSSTQ GAAERILLQE KRNCLLKQLE
EATRLATYLQ SQLKSLSAST LTVSSGSSRG SLASSRGSLA SSRGSLSSIS FTDIYGLPQY
EKTDALTDFS QHLRFDLIPF DAVCKDALHS DTVGLSNLSK QRRSLDTPQS LASLSSRSSL
SSLSPPSSPL DTPYLSASRD SPLAQMTEEF EEFTGRGALE NLRGQTHPGN EDTHGAASSQ
SPGYHRDNKG TKDVSPKLGS VAQGPSVVTL RTDSARRSGR RARRVSAGLS DDSLASDSGV
FEALNKRTED AEESVYNDAA SNEAPQIQVG TMYDSGNECL VVHVLHLKNF PAFTAKEGCR
IYIRVYLLPL DPSSTSTYCS KALEFQTQLT FSEAFRIPVH SSVLRLKSLQ LYVCSMDHQA
QEELLGLVQI SLPDPEGSSE MLLQWYLVQS FSSMETQKKR NSSQFGESSL ESTGNKTAVK
TDAVSALLAR TTAQLEAVER ELAEERVKLE YTEEEILEME RKEDLAEAES ERSWQAESVD
SGCSNSMQIS PNYPEGLCGE HGPGSVFGGQ VSQYVVVKAQ TPPTKVDKET NTEDPFPEEI
AVRPKERSNR RSRGSPFVRS STIVRSQTFS PGARSQYVCR LYRSDSDSST LPRRSPFIRN
TLERRTLRYK QQSYRSSLVE HPTRTSLDLE LDLQASRTRQ RQLNEDLSTL RELRQRLDEA
QLRGQTELPQ WVLRDERFRN LLREAERQAK QSQPERCQEQ AAERLLKKAS KEVFQLRGQN
QKEPQQVQTF REKIAFFTRP RINIPPLPAD DV
//
