ID H3A9N3_LATCH Unreviewed; 397 AA.
AC H3A9N3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Heterogeneous nuclear ribonucleoprotein K {ECO:0000256|ARBA:ARBA00018447};
GN Name=HNRNPK {ECO:0000313|Ensembl:ENSLACP00000006354.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000006354.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000006354.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
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DR EMBL; AFYH01201317; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01201318; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01201319; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01201320; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01201321; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006008965.1; XM_006008903.1.
DR AlphaFoldDB; H3A9N3; -.
DR Ensembl; ENSLACT00000006407.1; ENSLACP00000006354.1; ENSLACG00000005638.1.
DR GeneID; 102348860; -.
DR CTD; 3190; -.
DR GeneTree; ENSGT00940000153434; -.
DR HOGENOM; CLU_022670_5_1_1; -.
DR OrthoDB; 465127at2759; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000005638; Expressed in pelvic fin and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22432; KH-I_HNRNPK_rpt1; 1.
DR CDD; cd22433; KH-I_HNRNPK_rpt2; 1.
DR CDD; cd22434; KH-I_HNRNPK_rpt3; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 3.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR012987; ROK_N.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR Pfam; PF00013; KH_1; 3.
DR Pfam; PF08067; ROKNT; 1.
DR SMART; SM00322; KH; 3.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 3.
DR PROSITE; PS50084; KH_TYPE_1; 3.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022728};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00022728};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 38..106
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 116..187
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 320..390
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 43848 MW; A2E0634578003E7A CRC64;
METEQQETKF SNTETNGKRP AEDMEEEQAF KRSRNIDEMV ELRILLQSKN AGAVIGKGGK
SIKALRTDYN ASVSVPDSSG PERILSISAD IETIGEILKK IIPTLEEYQH YKGNDFDCEL
RLLIHQSLAG GIIGVKGAKI KELRENTQTT IKLFQECCPH STDRVVLIGG KPDRVVECIK
IILDLISESP IKGRAQPYDP NFYDETYDYG GFTMMFDDRG RRPMGFPMRG RGGFDRMPPG
RGVRPMPPSR RDYDDMSPRR GPPPSLTSRG GRGGSRTRNL PLPPPPPPRG DRRGRPGDRY
DGMGGSGYGG RCSYGDLGGP IITTQVTIPK DLAGSIIGKG GQRIKQIRHE AGASIKIDEP
LEGSDDRIIT IAGTQDQIQN AQYLLQNSVK QYSGCFF
//
