ID H3AB64_LATCH Unreviewed; 342 AA.
AC H3AB64;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
GN Name=LOC102360536 {ECO:0000313|Ensembl:ENSLACP00000006885.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000006885.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000006885.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; AFYH01224165; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006010958.1; XM_006010896.1.
DR AlphaFoldDB; H3AB64; -.
DR STRING; 7897.ENSLACP00000006885; -.
DR Ensembl; ENSLACT00000006944.1; ENSLACP00000006885.1; ENSLACG00000006111.1.
DR GeneID; 102360536; -.
DR KEGG; lcm:102360536; -.
DR eggNOG; KOG3656; Eukaryota.
DR GeneTree; ENSGT00950000182934; -.
DR HOGENOM; CLU_009579_11_0_1; -.
DR InParanoid; H3AB64; -.
DR OMA; GEFRYRT; -.
DR OrthoDB; 2901788at2759; -.
DR TreeFam; TF343107; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0001594; F:trace-amine receptor activity; IEA:InterPro.
DR CDD; cd15314; 7tmA_TAAR1; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR009133; TAAR1.
DR InterPro; IPR009132; TAAR_fam.
DR PANTHER; PTHR24247; 5-HYDROXYTRYPTAMINE RECEPTOR; 1.
DR PANTHER; PTHR24247:SF267; TRACE AMINE-ASSOCIATED RECEPTOR 4; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01831; TRACEAMINE1R.
DR PRINTS; PR01830; TRACEAMINER.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..310
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 342 AA; 38516 MW; 25D11625A8E80D5B CRC64;
MDSDGFEIPE GLFCYDVNGS CPKSIRPNSK RIPIYAAIGG TILITVCGNL VVIISIAHFK
QLHTPTNFLV MSMAVVDLLL GSMVMPYSMV RSVENCWYFG DIFCKVHSST DMMLCTASIL
HLCFVAVDRY YAVCNPLQYK AKITGFVVMM MITISWMLPA VVSFAVIFLG LHMKGVEEFY
NNHTKCTGGC VLFLNEASLV FGSMISFYVP GVIMVCIYGK IYLIASKQAR AIKGVANKAK
EASRSRISRN RERKAAKTLG IVMGDFLLCW FPYLFCNIMD PFLNYRTPPV LFEVLVWFAY
LNSTFNPIMY GFFYIWFREA LKIILFGKGF QCGSSTINLF SD
//
