ID H3AGX3_LATCH Unreviewed; 175 AA.
AC H3AGX3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Transmembrane protein 157 {ECO:0000256|ARBA:ARBA00041422};
GN Name=FAM174A {ECO:0000313|Ensembl:ENSLACP00000008894.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000008894.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000008894.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the FAM174 family.
CC {ECO:0000256|ARBA:ARBA00006986}.
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DR EMBL; AFYH01217835; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01217836; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006010435.1; XM_006010373.2.
DR AlphaFoldDB; H3AGX3; -.
DR STRING; 7897.ENSLACP00000008894; -.
DR Ensembl; ENSLACT00000008963.1; ENSLACP00000008894.1; ENSLACG00000007856.1.
DR GeneID; 102346683; -.
DR KEGG; lcm:102346683; -.
DR CTD; 345757; -.
DR eggNOG; ENOG502S4HB; Eukaryota.
DR GeneTree; ENSGT00730000111385; -.
DR HOGENOM; CLU_126641_0_0_1; -.
DR InParanoid; H3AGX3; -.
DR OMA; DTMEMAP; -.
DR OrthoDB; 5361958at2759; -.
DR TreeFam; TF105425; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000007856; Expressed in muscle tissue and 6 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR009565; FAM174-like.
DR PANTHER; PTHR28607; EXPRESSED PROTEIN; 1.
DR PANTHER; PTHR28607:SF1; MEMBRANE PROTEIN FAM174A; 1.
DR Pfam; PF06679; DUF1180; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..175
FT /note="Transmembrane protein 157"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003580302"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 32..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 175 AA; 18852 MW; 7193E497C37923F0 CRC64;
MATKQQQRSS CSLAWGLLIP LLLSAAAGLS STLPPAQKMD SSNRPSPPPV SGPGNASTKP
ALHPNSNNHN NNNSNKPMND TRAGSGGGGN LASVPGIPGS PERPMTQRAL CVLVIVSAAV
IVYFVIRTVR MRRKNRKTRR YGVLDTNIEN MELTPLEQED DDDDNTLFDA NHARR
//
