ID H3AJE8_LATCH Unreviewed; 504 AA.
AC H3AJE8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Discoidin, CUB and LCCL domain containing 1 {ECO:0000313|Ensembl:ENSLACP00000009769.1};
GN Name=DCBLD1 {ECO:0000313|Ensembl:ENSLACP00000009769.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000009769.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000009769.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR EMBL; AFYH01128845; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01128846; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01128847; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01128848; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01128849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01128850; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01128851; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01128852; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01128853; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01128854; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AJE8; -.
DR STRING; 7897.ENSLACP00000009769; -.
DR Ensembl; ENSLACT00000009844.1; ENSLACP00000009769.1; ENSLACG00000008613.1.
DR eggNOG; ENOG502QW5E; Eukaryota.
DR GeneTree; ENSGT00940000157334; -.
DR HOGENOM; CLU_016654_3_0_1; -.
DR InParanoid; H3AJE8; -.
DR OMA; DTQITGC; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000008613; Expressed in pectoral fin and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00057; FA58C; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.170.130.20; LCCL-like domain; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR004043; LCCL.
DR InterPro; IPR036609; LCCL_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR46806:SF1; DISCOIDIN, CUB AND LCCL DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46806; F5/8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF03815; LCCL; 1.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00231; FA58C; 1.
DR SMART; SM00603; LCCL; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF69848; LCCL domain; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS01285; FA58C_1; 1.
DR PROSITE; PS50022; FA58C_3; 1.
DR PROSITE; PS50820; LCCL; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00059};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 415..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..116
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 118..214
FT /note="LCCL"
FT /evidence="ECO:0000259|PROSITE:PS50820"
FT DOMAIN 221..378
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT REGION 380..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 4..31
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
SQ SEQUENCE 504 AA; 55644 MW; F058505285B4036F CRC64;
GEGCNHSVLT QDSGTLTSKN YPGTYPNYTS CKWRILVPQG KKIILKFGDL NIEAQQCESD
YLKIFTGSSA REYETYCGNE SSISEEFLLD TNELTLHFKS SSHISGRGFL LSYATSDHSG
LITCLDKANH YSEKEYRKYC PAGCKDIAGE VSGDSSEGYR HTSVLCKAAI HAGVITDELG
GQITVTQYKG LSQYEGIVAN GILSQNGSLS DKKFMFNNNG CANPLGMESG AISDRQITAT
SSWQWINENG ESIQWSMGKA RLRIQGPSWA AQHNSSQPWL QVDLTEQKQI TGILTTGSTL
SNFNYFVKTY KISYSENGQS WILYKSVGSN EEKIFEGNTD YLHLVRNNFI PPFVARSLRI
IPDTWNQRIA MKVELIGCPP GGPNSSPPLK PSLDTPTKDE DQNITEPVPS EELDLGLRLA
AIVVPAVLFL VLLVVGICIC GSLRKKKTKV DACSSDVQKT GCWKNLKQPF ARHQSTEFTI
SYNNEKETPQ RLDLVPCDMA GKGL
//
