ID H3AL07_LATCH Unreviewed; 647 AA.
AC H3AL07;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Stress-70 protein, mitochondrial {ECO:0000256|ARBA:ARBA00019355};
DE AltName: Full=75 kDa glucose-regulated protein {ECO:0000256|ARBA:ARBA00031419};
DE AltName: Full=Heat shock 70 kDa protein 9 {ECO:0000256|ARBA:ARBA00030055};
GN Name=HSPA9 {ECO:0000313|Ensembl:ENSLACP00000010328.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000010328.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000010328.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFYH01144091; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01144092; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01144093; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01144094; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01144095; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01144096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AL07; -.
DR STRING; 7897.ENSLACP00000010328; -.
DR Ensembl; ENSLACT00000010406.1; ENSLACP00000010328.1; ENSLACG00000009096.1.
DR eggNOG; KOG0102; Eukaryota.
DR GeneTree; ENSGT00920000149123; -.
DR HOGENOM; CLU_005965_2_4_1; -.
DR InParanoid; H3AL07; -.
DR OMA; MGTDWKI; -.
DR TreeFam; TF105046; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000009096; Expressed in muscle tissue and 6 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR HAMAP; MF_00332; DnaK; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR012725; Chaperone_DnaK.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR NCBIfam; TIGR02350; prok_dnaK; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR PANTHER; PTHR19375:SF184; STRESS-70 PROTEIN, MITOCHONDRIAL; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT COILED 530..603
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 647 AA; 70408 MW; 5AB9F438FC3E456F CRC64;
QGCFSGLGQD VLRVVSRRDY ASEAIKGTVI GIDLGTTNSC VAVMEGKQAK MERNLGGEKA
IGLNIVMTTG KRNLLKLGGF ALFITNAPVI VFYSTKSWVS SKHKNLETLP HSKNVPFKII
RASNGDAWVE AHGKMYSPSQ IGAFVLMKMK ETAENYIGHP IKNAVITVPA YFNDSQRQAT
KDAGQIAGLN VLRVINEPTA AALAYGLDKS SDKIIAVYDL GGGTFDISIL EIQKGVFEVK
STNGDTFLGG EDFDQALLQY LVKEFKRESG IDLTKDMMAL QRVREAAEKA KCELSSSLQT
DINLPYLTMD ASGPKHLNMK ITRSQFEGIV ADLIRRTVTP CQKALQDAEV SKSDVGEVIL
VGGMTRMPKV QQTVQDLFGR NPSKAVNPDE AVAIGAAIQG GVLAGDVTDV LLLDVTPLSL
GIETLGGVFT KLINRNTTIP TKKSQVFSTA ADGQTQVEIK VHQGEREMAS DNKLLGQFTL
VGIPPAPRGV PQIEVTFDID ANGIVNVSAK DKGTGREQQI VIQSSGGLSK DDIENMIKNA
EKYAEEDRRR KERVEAVNMA EGIVHDAESK MEEFKDQLPA EECNKLKEEI AKMRELLARK
DTETGENIKQ AASSLQQASL KLFEMAYKKM ASERENAGSG DKKEESQ
//
