ID H3AR85_LATCH Unreviewed; 424 AA.
AC H3AR85;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Metabolism of cobalamin associated A {ECO:0000313|Ensembl:ENSLACP00000012156.1};
GN Name=MMAA {ECO:0000313|Ensembl:ENSLACP00000012156.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000012156.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000012156.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB
CC subfamily. {ECO:0000256|ARBA:ARBA00009625}.
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DR EMBL; AFYH01066335; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01066336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01066337; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01066338; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005995602.1; XM_005995540.2.
DR RefSeq; XP_005995603.1; XM_005995541.2.
DR RefSeq; XP_005995604.1; XM_005995542.2.
DR AlphaFoldDB; H3AR85; -.
DR STRING; 7897.ENSLACP00000012156; -.
DR Ensembl; ENSLACT00000012248.1; ENSLACP00000012156.1; ENSLACG00000010701.1.
DR GeneID; 102345932; -.
DR KEGG; lcm:102345932; -.
DR CTD; 166785; -.
DR eggNOG; ENOG502QR2W; Eukaryota.
DR GeneTree; ENSGT00390000009908; -.
DR HOGENOM; CLU_043725_2_2_1; -.
DR InParanoid; H3AR85; -.
DR OMA; WMWERID; -.
DR OrthoDB; 159517at2759; -.
DR TreeFam; TF313243; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000010701; Expressed in pelvic fin and 6 other cell types or tissues.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd03114; MMAA-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR005129; GTPase_ArgK.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00750; lao; 1.
DR PANTHER; PTHR23408:SF3; METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL; 1.
DR PANTHER; PTHR23408; METHYLMALONYL-COA MUTASE; 1.
DR Pfam; PF03308; MeaB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
SQ SEQUENCE 424 AA; 46247 MW; 9DDDA2782EEA4159 CRC64;
MSAPSVLSKS LPWLCVLRLA RITSRNLHAG SKVGIGSDVG GRLTALPASP FNARLENPTA
RLPLLSDFKR LYVHAAVNHY PDGFTDKEQR VLNRLYEGLV RGQRACLAEA ITLIESTHHR
KKELAQVLIQ RVLAYHREQE SLKRGKPLAF RVGLSGPPGA GKSTFIEVLG KMLTGNGHKV
SVLAVDPSSC TTGGSLLGDK TRMHELSRDM NAYIRPSPTQ GTLGGVTRTT NEAIVLCEGA
GYDTVLVETV GVGQSEFAVA DMVDIFVLLI PPAGGDELQG IKRGIIEMAD LVVVTKADGD
LIVPARRIQA EYVSALKLLR KRSSVWKPKV MHISSRTGEG IPELWSKMSE FHSAVLSSGE
LIARRQKQQK VWMWNLIGEN VLEHFRKHPA VRDQIPLLED RVFNGVLSPG LAADILLKAF
AAGD
//
