ID H3ASM5_LATCH Unreviewed; 677 AA.
AC H3ASM5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=COP1 E3 ubiquitin ligase {ECO:0000313|Ensembl:ENSLACP00000012646.1};
GN Name=COP1 {ECO:0000313|Ensembl:ENSLACP00000012646.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000012646.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000012646.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01077449; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077450; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077451; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077452; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077453; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077454; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077455; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077456; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077457; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01077458; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3ASM5; -.
DR Ensembl; ENSLACT00000012740.1; ENSLACP00000012646.1; ENSLACG00000011141.2.
DR GeneTree; ENSGT00920000149161; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000011141; Expressed in pectoral fin and 6 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR CDD; cd16504; RING-HC_COP1; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR042755; COP1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR44080; E3 UBIQUITIN-PROTEIN LIGASE COP1; 1.
DR PANTHER; PTHR44080:SF1; E3 UBIQUITIN-PROTEIN LIGASE COP1; 1.
DR Pfam; PF00400; WD40; 5.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 95..133
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REPEAT 475..517
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 561..601
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 47..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 194..258
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 677 AA; 75520 MW; 3A0066AFC98487D4 CRC64;
PGQGSSGTAV PAAAPSSSSG AGRPGTSAGQ AAVTAAAAAS GSGVGLARVG AGRAGSSSSS
SSSSSQSGSR KRPLLTPLCN GLLNSYEDKS NDFVCPICFE MIEEAYMTKC GHSFCSKCIR
QSLEDSNRCP KCNYVVDNID QLFPNFLVNE LILKQKQRFE DKRLKLDHSN SSRNGHKWQI
FQDVLGTDQE SLDLAKINQI LELLVQKKKQ LEAESQAAQL QILMEFLKEA RRNKREQLEQ
IQKELSVLEE DIKRVEEMSG LYSPVSEIDQ SQNLDSTVPQ FEAPSPSHRS IIDSTEYTQH
PGFSGTSQGK RQPWYNSTLA SRRKRLTAHF EDLEQCYFST RMSRISDDSR IVNQLDEFQE
CLAKFTRYNS VRPLATLSYA SDLYNGSSIV SSIEFDRDCD YFAIAGVTKK IKVYEYGTVI
QDAVDIHYPV IEMTCNSKIS CISWSSYHKN LLASSDYEGT VILWDGFTGQ RSKVYQEHEK
RCWSVDFNLM DPKLLASGSD DAKVKLWSTN LDNSVASIEA KANVCCVKFS PTSRYHLAFG
CADHCVHYYD LRNTKQPIMV FKGHRKAVSY AKFVSGEEIV SASTDSQLKL WNVNKPHCLR
SFKGHINEKN FVGLASNGDY IACGSENNSL YLYYKGLSKT LLTFKFDTVK SVLDKDKKED
DTNEFVSAVC WRARPDG
//
