ID H3AXV1_LATCH Unreviewed; 424 AA.
AC H3AXV1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN Name=CHST2 {ECO:0000313|Ensembl:ENSLACP00000014472.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000014472.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000014472.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc
CC subfamily. {ECO:0000256|ARBA:ARBA00005530}.
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DR EMBL; AFYH01135256; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006002851.1; XM_006002789.2.
DR AlphaFoldDB; H3AXV1; -.
DR STRING; 7897.ENSLACP00000014472; -.
DR Ensembl; ENSLACT00000014572.1; ENSLACP00000014472.1; ENSLACG00000012735.1.
DR GeneID; 102353816; -.
DR KEGG; lcm:102353816; -.
DR CTD; 100006249; -.
DR eggNOG; ENOG502QTSD; Eukaryota.
DR GeneTree; ENSGT00940000161292; -.
DR HOGENOM; CLU_028381_1_0_1; -.
DR InParanoid; H3AXV1; -.
DR OMA; KWRREPR; -.
DR OrthoDB; 3031241at2759; -.
DR TreeFam; TF342871; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000012735; Expressed in pharyngeal gill and 4 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR016469; Carbohydrate_sulfotransferase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10704; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR10704:SF3; CARBOHYDRATE SULFOTRANSFERASE 2; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR PIRSF; PIRSF005883; Carbohydrate_sulfotransferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|RuleBase:RU361155};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022968}.
FT DOMAIN 223..400
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 424 AA; 48639 MW; 68E119E776AE933B CRC64;
MMKILRRKGV ILFIGYVLLL ILTMLNLVDY KWTKEPQQCN DQVRHTPYQT RSDIRYLYRQ
QPARKRQLVY VFTTWRSGSS FFGELFNQNP ETFFLYEPMW HIWQRLYPGD AISLQGAARD
MLSSLYRCDL SVFQLYNSPG SKNITSLGIF GAATNKVVCS EPLCSAYRKD MVGMVDDKIC
KKCPPQALSS LERECLKYNT IVVKGVRILD INVLAPLMED PSVNLKVIHL VRDPRAVANS
RIKSRHGLIR ESLQIVRSRD PKARRIPFID PNHKINKKDG SDYHAVGAME VICSTTTKIL
QTALKPPDWL KGKYMAVRYE DLVENPIKTL KQVYGFVNLS VSHDIEKFAL NMTSGSSYSP
KPFVVSSRNA TQAVSAWRTL LTYQQIKQVE EYCQQTMALL GYERVATPEE VKDLSKTLLT
KSRV
//
