ID H3BB17_LATCH Unreviewed; 539 AA.
AC H3BB17;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000019088.1};
GN Name=RNF135 {ECO:0000313|Ensembl:ENSLACP00000019088.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000019088.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000019088.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01051081; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01051082; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01051083; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BB17; -.
DR Ensembl; ENSLACT00000019221.1; ENSLACP00000019088.1; ENSLACG00000016797.1.
DR GeneTree; ENSGT00940000154294; -.
DR HOGENOM; CLU_013137_0_1_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000016797; Expressed in pharyngeal gill and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19802; Bbox1_TRIM8-like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF31; RING-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 14..55
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 356..539
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 181..215
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 539 AA; 60202 MW; DDCC0014114F554D CRC64;
SMAAFSAAAE DLNCAICCEL FDNAVSLNCG HSFCRQCIEQ HWEKRAGGGY TCPLCMKAFR
EKPELNKNTV LCALAERCRA GQGQAAACGS EVCCSFCPSS PDSKADRTCL TCRASYCAVH
LKPHLEVAAL KEHLLVAPVE LTEKQCQLHG GMLAFHCKSD KGLLCSQCFA LHQECEIVSI
EEELREKIGR VKVTIEKLSN AIQSVEGAIS KRNQERTMVQ ESATQMKALL KTKFTELMTC
IEKQGRAALR AVEHEERATQ EKISGIINQL ADKAVELKKA KVHIEQLEHE DWQTLLKKYK
FFSLLSCFED LNLIYSPSFL QGNGGILSQL SQPQKSLNTF LAGWSCSNRG SSISTVIISL
VPAICWSKAE YCTVKLTFDS STANRYLRLE RNNVTVTSQL HHPSDVNRFA VSQVMCLEGF
SSGRHSWKVN TEKSGGWAIG IAYKPIDKAV YLGRNSRSWC LEYSNKRLSA WHSRCEIPLD
HPKPCTVIVE LDYIEGKLSF YSITETATLL HTFEAVFTQS VFPAFWLYGL EKQNTLILN
//
