ID   H3BEX0_LATCH            Unreviewed;       761 AA.
AC   H3BEX0;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Fibronectin type III and SPRY domain containing 2 {ECO:0000313|Ensembl:ENSLACP00000020441.1};
GN   Name=FSD2 {ECO:0000313|Ensembl:ENSLACP00000020441.1};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000020441.1, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000020441.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AFYH01020552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H3BEX0; -.
DR   Ensembl; ENSLACT00000020581.1; ENSLACP00000020441.1; ENSLACG00000017964.1.
DR   GeneTree; ENSGT00940000158441; -.
DR   HOGENOM; CLU_022856_0_0_1; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   Bgee; ENSLACG00000017964; Expressed in muscle tissue and 4 other cell types or tissues.
DR   CDD; cd00063; FN3; 2.
DR   CDD; cd12899; SPRY_PRY_TRIM76_like; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR   PANTHER; PTHR24099:SF6; FIBRONECTIN TYPE III AND SPRY DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF00041; fn3; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM00060; FN3; 2.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50853; FN3; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT   DOMAIN          384..479
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          480..574
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          556..757
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   COILED          268..295
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   761 AA;  87213 MW;  C45DDAFDB5F88A6A CRC64;
     TQEDAGEKEP EGLTFYHMDL YESQERLDIF AEEQAAASGR TDQFDITEYG EFKRGEQDLG
     FSQTVGDIYA EDVEELARQY GLTDDKEIEM ELPTESPLDV FKRRHEQYNE QYQIPEQDYI
     EQDIELNSFK TTDKIPEYIS SGEDFLTSRE MEQYQHIYTD VDTREMTHLK QEIEIQATTE
     NEIPDVFCVV CKVPIRAFDK LFGPHKDHEV AQLDKAVEDE KVELHTNMCK LEEQIAQMEN
     FASHLEEIFI TVEENFGRQE QNLEQHYNEV MQILAQRYEE KIQGLGEEKK QKLETLYGHL
     VNCGKALDTS KELTETTQEL CKEEDKVTFL KNAVATMDRL EEFFKTDDNM GDSTIAEFQN
     CTIDFSDVKQ LMDSINTVPA PSAPVINPQN PNSATSTSVR VCWSLFSDDT VECYQLYYKQ
     VIEDTTGEEQ NERMVKVKET YCTVNDLVPN TQYEFWVTAL NTTGISPASE RAVYMTVPSP
     PIVKCKECRS CQQAALICWE SGNTNPVDSY TVELCKLTNE ENESVVTESI VGVPTCESLI
     QLQSGQSYII YVRAVNVGGP SERSQPVTIH TTGTFFHLNE DTAHPLLVIL EDGFTIAYNE
     EESISCDLSF NDNSFTNNRC IAIMGSLIPV RGKHYWEIEV DETTEYRVGV AFEDTQKNGY
     LGGNNTSWCM RHIITPSRHK YEFLHNGSTP DVRITDPPKR VGILLDYDTG RLSFFNSYLC
     QHLFTFKCQF QHFVHPCFAL EKSGVLQIRN GIAAPEYVKF T
//