ID H3BHH9_LATCH Unreviewed; 910 AA.
AC H3BHH9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Adhesion G protein-coupled receptor D1 {ECO:0000313|Ensembl:ENSLACP00000021350.1};
GN Name=ADGRD1 {ECO:0000313|Ensembl:ENSLACP00000021350.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000021350.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000021350.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AFYH01006684; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006685; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006687; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006688; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006689; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006690; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006691; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006692; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006693; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3BHH9; -.
DR STRING; 7897.ENSLACP00000021350; -.
DR Ensembl; ENSLACT00000021491.1; ENSLACP00000021350.1; ENSLACG00000018761.1.
DR eggNOG; KOG4193; Eukaryota.
DR GeneTree; ENSGT00940000159783; -.
DR HOGENOM; CLU_008509_0_0_1; -.
DR InParanoid; H3BHH9; -.
DR OMA; PANTVMP; -.
DR TreeFam; TF351999; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF216; ADHESION G-PROTEIN COUPLED RECEPTOR D1; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..910
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003581314"
FT TRANSMEM 605..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 640..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 670..688
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 709..728
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 748..774
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 795..816
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 822..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 602..846
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 910 AA; 101355 MW; 8F1CED8B44D21B1A CRC64;
MEKFLLCFCF NIFLVLLYCN TQVYGNHTLT NHPGFQILAS ASHYWPLDMV NGITELQTEN
GGQTAVRIHN FTVLPFHNST FVYTNDSAYS NLSATVDIVE GTVNNGIYLR RDTGDIFLHF
GNYRNSCISD PMLCGPKGVT FSFFWKIQEG QSRPTMASGG SVISSVFCVY SKVSDSYVEF
YTHGNSHSWK AKIKPPDPYW THILFTWTQG DGLKVYINGT LYTNDTKGEV SQNYGDPGGI
NLVITTENEQ PYGYHVTGAF DEFVFWEKSL SPEEIRLYFK AAIGESGFPS STSSWLNTTS
ATTHPVVSTN AYHPIITNLT EERHNFQYPV PMLGFLESMS LNLPNKTLSQ ETASNLTETF
LKTVEEVISL PSWSDVAETT SVVGGLIETI DKVMMHMAQN VAVTSSSVMS IEGTSSVADY
SLVKVPKSIN LHHYRFPSQG RSYISVPGEA FHSKTQTTII GLLYHSVHNY YKKINPLNTK
IAEAAQYKDY EISATSYLIS LKVHPPPALS HNLSGSPLIT IVLTHMLSLK QRSQAINKTN
HIFLYCAFLD YRSGFGVWSN EGCIRTGGNL SYSICLCNHL TNFAILMQVV PLELAYGHQV
ALSSISYIGC SISIFCLTIT LVTFAILSSV STIRNQRYHI HANLSFAILT AQILLLISFR
FDPGTMPCKI MAILLHFFFL GAFAWMLVEG LHLYSMVIKV FGSEESKHFY YYGIGWGSPL
VICIVSVTSA LDSYGEEGNC WLSLEKGAIW AFVAPALFVI LVNIVILIAV TRIISRISAD
NYKVHGDANS FKLTAKAVAV LLPILGSSWI FGVLAVNDKA ILFQYVFAIF NSLQGFFIFL
FHCLLNSEVR AAFKHKTKVW SLTSSSIRNI NVKPFNSDIM NENRQGTTPT KLNTWDKSTN
SANRIDLSAV
//
