ID H3C5W4_TETNG Unreviewed; 552 AA.
AC H3C5W4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Insulin-like growth factor binding protein, acid labile subunit {ECO:0000313|Ensembl:ENSTNIP00000003634.1};
GN Name=IGFALS {ECO:0000313|Ensembl:ENSTNIP00000003634.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000003634.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000003634.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H3C5W4; -.
DR STRING; 99883.ENSTNIP00000003634; -.
DR Ensembl; ENSTNIT00000003270.1; ENSTNIP00000003634.1; ENSTNIG00000001418.1.
DR GeneTree; ENSGT00940000160824; -.
DR HOGENOM; CLU_000288_18_6_1; -.
DR InParanoid; H3C5W4; -.
DR OMA; TFLHTQN; -.
DR TreeFam; TF351124; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR PANTHER; PTHR24373:SF275; VASORIN; 1.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF13855; LRR_8; 4.
DR Pfam; PF01462; LRRNT; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00365; LRR_SD22; 6.
DR SMART; SM00369; LRR_TYP; 17.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 9..47
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
SQ SEQUENCE 552 AA; 62114 MW; 1252068476069C72 CRC64;
SPSGREGPRC PSGCTCQQDD YSLELTVYCS AQNLTQVPAN IPPSTHSLWL DLNLFTSLPP
ASFKDLLHLE FLNLQSGQLA TLDPQALRGL RSLAHIHLER NRIRALPASI FQNTPNLASL
SLHNNQLSRI DDRLFAGLSH MWLLNLGRNS IAVLPETVFQ DLQGLRELIL AGNRLAYLQP
QLFQNLVELK ELDLSGNQLK VIKANVFVKL TKLQKLYLAQ NQIATVVPRA FVGMKSLRWL
DLTNNRLGSL HEDTFMGLYH LHVLRLSNNS IAGLRPRTFR DLQYLEELRL SHNRIRVLTE
KVFEELGRLE VLELEHNRIQ EAKAGSFAGL SYVAVINLSG SCFQVLPDQM FRGLSKLHSL
HLDRGCLTRV TAQAFSGLSS LRRLFLQRNN ITAVERQSFA ELVGLLGLDL SFNKLEVITG
QMFSGLKNLE YLLLSNNDCR QFLQNGTKLL LPRLRYLDLS ANELTSIVPE FAEGLEKLLL
SGNRWRCDCG ALALRNYSLR NPLVVPRQVK THAEGEEPDR TITIYNNVTC NSPAHVSGQD
LRDIEGAVFQ SC
//
