ID H3CCP1_TETNG Unreviewed; 961 AA.
AC H3CCP1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=SH3-domain binding protein 4a {ECO:0000313|Ensembl:ENSTNIP00000006014.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000006014.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000006014.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC {ECO:0000256|ARBA:ARBA00004132}. Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004600}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
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DR AlphaFoldDB; H3CCP1; -.
DR STRING; 99883.ENSTNIP00000006014; -.
DR Ensembl; ENSTNIT00000006162.1; ENSTNIP00000006014.1; ENSTNIG00000003427.1.
DR GeneTree; ENSGT00390000013151; -.
DR HOGENOM; CLU_013080_2_0_1; -.
DR InParanoid; H3CCP1; -.
DR OMA; FMITSHN; -.
DR TreeFam; TF105572; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR15603:SF3; SH3 DOMAIN-BINDING PROTEIN 4; 1.
DR PANTHER; PTHR15603; SH3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51145; ZU5; 1.
PE 4: Predicted;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Membrane {ECO:0000256|ARBA:ARBA00023176};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 57..116
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 320..454
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT REGION 331..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 961 AA; 106458 MW; C61E47394245A961 CRC64;
MAAHRIIRAT NSSHILPRCK SEGTLIDLSE GVGGASLSDV KVPSPSALRL DTSASYGAVQ
EVVAIKDFCP SSFTTLSFSK GDHLYVLDTS GGDWWYAHNN TEMGYIPAAY VQPLHLRNSS
LSDSGMIDSL GDGYEDGSKE AGDLGEWSGM MERQPSGFSG SSPFSGNPFV CPLDQNCDAV
RGKTPAELLL FDPLGSPLSC SSLHTGPALS NGIGSSGDIV SFEAAGPSQE AGPSLRENLL
FRSKRSHSLS ELSALQARAE PALPPSGFFT GLKAPSPEQF ENREEFRTAW LNHRKLARSC
HDLDSLGLSP GWGQTQPVET SIVCRLDATG RSGAASRHPH QRPRPRSHVG PGDHQQISLK
ALLDPPLELN SDRCSTLSPV VELKLSNMET KSFITLEMKV FVTVTKESFQ CAPLLCRSDC
KEGPYSPVPN AYVYKDTVQV QLDSLEPCMY VAVVVQSAAA PAGAFWDHVQ RKVTLGVYGP
KHVHPAFKAV VALFGHDCAP KTLLVSEEGR HARSNPPVAL QLWGRHQFLL GFPQDLRVGL
YSNMSNYQVD AGDGAGLIQG FQVKLGKVCR LLFMITSHNP ANISDFTLRV QVKDALDCIL
TQFCVQTPPP PPKTGPRITG QRRFLKKREV DKIVLSPLAV TSKYPKFQDR CVTNLRFGKV
IKTVIRQHKS TYLLEYRKGD VLALLSEEKI RLRGQLRTKE WYIGYYQGRI GLVHAKNVLV
LGKVKPIYWC GPDLTTTLLL EQILKPCKFL TYIYATVRTV LMENIGNWRA FADALGYGGL
PLSYFCRSEL DNEPERVASV LEKLKEECMN AENKERKSFQ RELMMALLKM DCQGLVARLV
DFVLLTTAVE VAPRWRELAE KLARVSRQQM EAYEAPHRDK DNLLDNECMW KPAYDFLLTW
AAHIGDSYRD VIQELHVGLD RMRNPITKRW KHLTGSLILV NCLDSLRSSA FCPVGYGDFA
V
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