ID H3DC40_TETNG Unreviewed; 464 AA.
AC H3DC40;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Plakophilin 1 {ECO:0000313|Ensembl:ENSTNIP00000018083.1};
GN Name=PKP1 {ECO:0000313|Ensembl:ENSTNIP00000018083.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000018083.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000018083.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR AlphaFoldDB; H3DC40; -.
DR STRING; 99883.ENSTNIP00000018083; -.
DR Ensembl; ENSTNIT00000018307.1; ENSTNIP00000018083.1; ENSTNIG00000015032.1.
DR GeneTree; ENSGT00940000156735; -.
DR HOGENOM; CLU_009111_4_0_1; -.
DR InParanoid; H3DC40; -.
DR OMA; GVKWLCH; -.
DR TreeFam; TF321877; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR028435; Plakophilin/d_Catenin.
DR PANTHER; PTHR10372:SF3; PLAKOPHILIN-1; 1.
DR PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR Pfam; PF00514; Arm; 3.
DR SMART; SM00185; ARM; 5.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT REPEAT 47..89
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 464 AA; 50769 MW; 4C48B5910F3EAE94 CRC64;
SWFQTDLERA VEYLSHPDES YQQCGATSIQ HTAFNEEQAK QEVLKLGGIP GLVSLLRSPN
PNVSLAAAGA LRNLVFKHQY NKLEVQHCGG IAKALQLLKE TNSTETQKQI TGLLWNMSSS
DDLKAELIAT ALPALTENVM VPFTCWSDDT NNNNIHPDVF HNATGCLRNL SCGKQKARQA
MRDCCGLIDS LMSYIQSCIA EENPDDKSVE NCVCILHNLT YQLEAERPQC FGKYQPKTDS
EFDRQKSPIG CFSPKSTKAQ KEVLSQFSFD VTKMPEETTS SGVNWLCHPT AMHSYLSLLG
SSQKDATLAA SCGVLQNLTA SKQPVSRNEI TEILVRKLGA LAHISSLLKS PNLSLQKKAL
SLLANMSRTS CLQTSMAKQI LPDLISRLSN PGAVTDDVIA PACNTAGTLM LADTEFSKKM
VTKELVSGLA DLSEDDSFPK GSRAASLLLY SMWNDKNLQA AVKK
//
