ID H3DDH7_TETNG Unreviewed; 2763 AA.
AC H3DDH7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Centrosomal protein 350 {ECO:0000313|Ensembl:ENSTNIP00000018570.1};
GN Name=CEP350 {ECO:0000313|Ensembl:ENSTNIP00000018570.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|Ensembl:ENSTNIP00000018570.1, ECO:0000313|Proteomes:UP000007303};
RN [1] {ECO:0000313|Proteomes:UP000007303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|Ensembl:ENSTNIP00000018570.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 99883.ENSTNIP00000018570; -.
DR Ensembl; ENSTNIT00000018797.1; ENSTNIP00000018570.1; ENSTNIG00000015499.1.
DR GeneTree; ENSGT00940000155130; -.
DR HOGENOM; CLU_000421_0_0_1; -.
DR InParanoid; H3DDH7; -.
DR OMA; ESKHIYC; -.
DR TreeFam; TF329845; -.
DR Proteomes; UP000007303; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR028750; CEP350/CC187.
DR PANTHER; PTHR13958; CENTROSOME-ASSOCIATED PROTEIN 350; 1.
DR PANTHER; PTHR13958:SF7; CENTROSOME-ASSOCIATED PROTEIN 350 ISOFORM X1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007303}.
FT DOMAIN 2198..2240
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 47..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 300..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 881..968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1009..1041
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1175..1269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1314..1353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1694..1752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1836..1946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1982..2014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2026..2086
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2276..2307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1403..1487
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 56..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..546
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 888..902
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 903..917
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 918..954
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1175..1201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1202..1246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1249..1265
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1314..1347
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1836..1884
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1885..1918
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1919..1935
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1994..2014
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2039..2055
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2288..2307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2763 AA; 309252 MW; E753AF4B16065C38 CRC64;
TRDKNKEGSV DSKDSSSSQC TDIRYINDQP ALDRLVTVGQ SQLRVLLRER TEEGSSPEAQ
SGADNLDSSP CAATGTMNLG QSIPSSSPGS ASQRLENLRR HQHDEKLEKL RERIRRQRQH
LPEAAEREKL FGHLERPIAT SYTNNSADCS NVAKIRKVAP APPPPVYKGF NSTETKIQTP
DGKVWKEQEF QDLSREIYRD LSRQFSGQKQ QREHGVDSSK ERLPTKPVRK VHTVASTSDP
NTQPSSQHLQ LSVVHHGEKD QRRVLGPVPK LPQDDRSQPL RGHSRAGNVF CFFSPSLTAP
HHSPTDSQLQ SHSDTTEHPS TGVKSQKKRN SIPSSTELSK PRAGGTAESL SADIQGILDD
LQFECKMPEK EEKTLQKIRD AMCSTSRGCR SASPSARQKE SARANDVTQK KRHYDADTVR
QYISRQKEER KRRQVEEKRA LKEQEERRHQ RLQELYRKQK EVAKAASLPS EAPTHDSLQG
TYIKLTEEAR VEERPTSTQI TASQMRPIYQ PSGESDKENK RLGAPRSPSS SDRSLSGQQP
LPLSTNDLDV TPLFEPHHLS PAGRPATDPR SDHFLSQLLR LEPALTVGDI NPVQHPATVP
SSRSRKKMSR IEFIKSTAAS LSNRLEYEAR RLAGEGINYG TVTSVDVDTA MAPEPSQGVD
DDQWWIKTTA TEKNDMLGHR TNRGHASYND TDLPGVVSLH AFSGQKEMNL PSHADVAAQP
SPKSQKHERE MPKRIDKMPQ LQEYEMIAEK GHTDALDSSA GSISEGPLLS EGSFSEDEAV
SPHFKTAAHQ LDVHGHCAGQ PKECQRLSEF QKEAARLSAA NLVFGQHGGT KSRLGKGSPM
SIVNIFTRNL QGRVRVNERI SPSEKFSVQN AHTPVDAVYE DDFESSPNSE ANDQSKRSSN
LRKSICRASD HSDATLVDEQ RSSCSPPSEP LSFESWKRGS NRSSVNPSKS VHSTDISERS
FHKRGPQDCW SSQLTPKFWP TVKGNFSYLD LFNVSLHFLV DSKKTRAAQS KQVSVSSSRT
MGSDSPVTSS PNTCSSPHSG KQQTHAAETR IFLVLLCCIS PHLSLILGDL QYSPAALQQR
MAAELQYLES IEESIRQLGD VERLLGVSTA QQESVSLAQM LQIHILILHL HITSYMMVVF
GFLNDLYYMT ELARSQITGA VGGPTTAADS SLLEKHDKHE NSHAKHQQAK SHSERKGKPE
DTSSTMNSPS DSYSSFRKTM HSGENSGSPS HASLDCEKQI SNHVPQGKLR QKGAEEIKES
EAGSSSIEEE VLTAENNSLC SENIPSVNEK VENTLAETEY SLKFDESMTE DEIEEHSFRS
LLPSEAHRRG TKDKSRHQDE SEDDGPSDRP MFSTLADANM AFSSGQNSFS QFTMDMVRQY
MKDEQVRLHH QSSLLHLRQK ALKEKTKTEL AWLEHQKKRL RDKGEDDKMP PIRKKQRGLL
MKHQQEQAEI RRLQEANKAA RKESQLLLKQ QEEIERMRNS TLKLRERLKI AGGDPPPETP
VSETPASEVA ASTMRYAKDI RSLSPSPSVS GSETSSIMQK LRKMRSHMDE NFIPKSLHQT
KRVAIVSKTK LEFRKRNLKR SGCSIRPFAH VTLLSPFSFY MFPSLINPYS LYLQPVGQVL
YIAQYFFPST FTYSHPLEHA CVLLALGSLM VEWVTLSQSL LGSQRSGSPS SVQSLPVTET
HLASIQESPA NYTQDFTSAS QSNVKQSPQF SSRGSNSPTA SPSERSNKTQ SNNQAHTQPT
DSRRISQSEL ISDQSDIETR IKALKEELKK RKFMAYQLKK EQKKRHKERL KAQEANLLKQ
LQSYDKFIEK TKAELDKEPD ATNSTDALHQ LDHSTAVPNA ETVTPSSVHD NPESLNSGPK
SCPSTGLLRP SSGEAQMIES GDESSVSYRR SDLQEETVHD VRSRSEDQQL EQNLKLEKED
SLQSISTSQH IQGDFPPGSP KQDNKIRKND ISKVKEAEMS DIIASAVSDL SENCELATHL
NSTLSSGDHS RSHNLGLISK KEDSKKDAKA SSSIANEYDD DFELSVCSSP REEHHSSNPA
SHTSTSPAEG KGSSVHLSSQ DEEIEEEIDE ELEQFSETSK GSNQSERLLD LLNKREDSIQ
EGEDTSPMTP KTEKLLMSEL EESLPQTFSE ALGIPDEVDN LRLKTLTGII HEEKSSEKSK
SFIVPLPRRS RGEAGAPTHV ASKVSITSPT SQVIKGSRST SFVMRFWAGV ELDKSEGSNN
GTYDGVLYFV CEENHGIFAP PNKITHLPDK FEVYTDTTED EESFFDDLPG ERGLKCKPVK
DKFPNQNLMK ENDQTSQDVI DESKNNNVST GSVFQAELDL NSNSGNDSDH PISNCHIEDA
ILDLQDLPHN HQTSGTDIDV QQKQSPKEVN NLEETVVPFQ EGKIASHLTT GITNEGTQEK
EKVSLDTFAD TLLNSFVHDI VKQCAEIKKG KEQKIEAENR TNGDLFAESG EEKIERPVEN
KDGLPFFLPA EQEELSSPEL CNRPESPVFG PSGQEELAKR LAELELSREL LDDIGDDQDW
FDEDFGLSSR KEQERLRKPE LPLPLPPQLP ELPAMVVPHS AAELEKMVYT ATQEIWEVCG
LGKNGMLIQA HLPVPKPSQD YLGEEASGSD QEAVCIRSYK KAVFDFTWEI LQDIYAEDPN
IDQPQWMKPR RVKSYYRVKT RGDVTKTQEF IAAEVLKLYG LTKDQSQKTD WQKMLKFGRK
KRDRVDQILV QELHEEEAQW VNYDEDELFV KIQLADSIFD ALLKDTVNVL NEIYEKKAKR
KAS
//
